Literature DB >> 26913221

Long Term Societal Costs of Anterior Discectomy and Fusion (ACDF) versus Cervical Disc Arthroplasty (CDA) for Treatment of Cervical Radiculopathy.

Ahmer Ghori1, Joseph F Konopka1, Heeren Makanji1, Thomas D Cha2, Christopher M Bono3.   

Abstract

BACKGROUND: Current literature suggests that anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA) have comparable clinical outcomes for the treatment of cervical radiculopathy. Given similar outcomes, an understanding of differences in long-term societal costs can help guide resource utilization. The purpose of this study was to compare the relative long-term societal costs of anterior cervical discectomy and fusion (ACDF) to cervical disc arthroplasty (CDA) for the treatment of single level cervical disc disease by considering upfront surgical costs, lost productivity, and risk of subsequent revision surgery.
METHODS: We completed an economic and decision analysis using a Markov model to evaluate the long-term societal costs of ACDF and CDA in a theoretical cohort of 45-65 year old patients with single level cervical disc disease who have failed nonoperative treatment.
RESULTS: The long-term societal costs for a 45-year old patient undergoing ACDF are $31,178 while long-term costs for CDA are $24,119. Long-term costs for CDA remain less expensive throughout the modeled age range of 45 to 65 years old. Sensitivity analysis demonstrated that CDA remains less expensive than ACDF as long as annual reoperation rate remains below 10.5% annually.
CONCLUSIONS: Based on current data, CDA has lower long-term societal costs than ACDF for patients 45-65 years old by a substantial margin. Given reported reoperation rates of 2.5% for CDA, it is the preferred treatment for cervical radiculopathy from an economic perspective.

Entities:  

Keywords:  anterior cervical discectomy and fusion (acdf); cervical disc arthroplasty (cda); cervical radiculopathy

Year:  2016        PMID: 26913221      PMCID: PMC4752013          DOI: 10.14444/3001

Source DB:  PubMed          Journal:  Int J Spine Surg        ISSN: 2211-4599


  27 in total

1.  Long-term results after anterior cervical discectomy and fusion with allograft and plating: a 5- to 11-year radiologic and clinical follow-up study.

Authors:  Wai-Mun Yue; Wolfram Brodner; Thomas R Highland
Journal:  Spine (Phila Pa 1976)       Date:  2005-10-01       Impact factor: 3.468

Review 2.  Recommendations of the Panel on Cost-effectiveness in Health and Medicine.

Authors:  M C Weinstein; J E Siegel; M R Gold; M S Kamlet; L B Russell
Journal:  JAMA       Date:  1996-10-16       Impact factor: 56.272

3.  Medicare program; revisions to payment policies under the physician fee schedule, DME face-to-face encounters, elimination of the requirement for termination of non-random prepayment complex medical review and other revisions to Part B for CY 2013. Final rule with comment period.

Authors: 
Journal:  Fed Regist       Date:  2012-11-16

4.  Cervical disc arthroplasty versus fusion for single-level symptomatic cervical disc disease: a meta-analysis of randomized controlled trials.

Authors:  Hua Jiang; Zezhang Zhu; Yong Qiu; Bangping Qian; Xusheng Qiu; Mingliang Ji
Journal:  Arch Orthop Trauma Surg       Date:  2011-10-09       Impact factor: 3.067

5.  Factors affecting the incidence of symptomatic adjacent-level disease in cervical spine after total disc arthroplasty: 2- to 4-year follow-up of 3 prospective randomized trials.

Authors:  Pierce D Nunley; Ajay Jawahar; Eubulus J Kerr; Charles J Gordon; David A Cavanaugh; Elisa M Birdsong; Marolyn Stocks; Guy Danielson
Journal:  Spine (Phila Pa 1976)       Date:  2012-03-15       Impact factor: 3.468

6.  Health outcome assessment before and after anterior cervical discectomy and fusion for radiculopathy: a prospective analysis.

Authors:  G R Klein; A R Vaccaro; T J Albert
Journal:  Spine (Phila Pa 1976)       Date:  2000-04-01       Impact factor: 3.468

7.  Epidemiology of cervical radiculopathy. A population-based study from Rochester, Minnesota, 1976 through 1990.

Authors:  K Radhakrishnan; W J Litchy; W M O'Fallon; L T Kurland
Journal:  Brain       Date:  1994-04       Impact factor: 13.501

8.  Comparison of BRYAN cervical disc arthroplasty with anterior cervical decompression and fusion: clinical and radiographic results of a randomized, controlled, clinical trial.

Authors:  John G Heller; Rick C Sasso; Stephen M Papadopoulos; Paul A Anderson; Richard G Fessler; Robert J Hacker; Domagoj Coric; Joseph C Cauthen; Daniel K Riew
Journal:  Spine (Phila Pa 1976)       Date:  2009-01-15       Impact factor: 3.468

9.  Results of the prospective, randomized, controlled multicenter Food and Drug Administration investigational device exemption study of the ProDisc-C total disc replacement versus anterior discectomy and fusion for the treatment of 1-level symptomatic cervical disc disease.

Authors:  Daniel Murrey; Michael Janssen; Rick Delamarter; Jeffrey Goldstein; Jack Zigler; Bobby Tay; Bruce Darden
Journal:  Spine J       Date:  2008-09-06       Impact factor: 4.166

10.  A meta-analysis comparing the results of cervical disc arthroplasty with anterior cervical discectomy and fusion (ACDF) for the treatment of symptomatic cervical disc disease.

Authors:  Yu Gao; Ming Liu; Tao Li; Fuguo Huang; Tingting Tang; Zhou Xiang
Journal:  J Bone Joint Surg Am       Date:  2013-03-20       Impact factor: 5.284

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  6 in total

1.  Editorial on "Long-term clinical outcomes of cervical disc arthroplasty: a prospective, randomized, controlled trial" by Sasso et al.

Authors:  Heeren S Makanji; Kenneth Nwosu; Christopher M Bono
Journal:  J Spine Surg       Date:  2016-12

Review 2.  Cost-effectiveness of anterior surgical decompression surgery for cervical degenerative disk disease: a systematic review of economic evaluations.

Authors:  V N E Schuermans; A Y J M Smeets; A F M Boselie; O Zarrouk; S M M Hermans; R Droeghaag; I Curfs; S M A A Evers; H van Santbrink
Journal:  Eur Spine J       Date:  2022-02-28       Impact factor: 2.721

3.  Cervical Artificial Disc Replacement Versus Fusion for Cervical Degenerative Disc Disease: A Health Technology Assessment.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2019-02-19

4.  Clinical Outcomes of Single-Level Anterior Cervical Discectomy and Fusion.

Authors:  Steven R Niedermeier; Sohrab S Virk; Safdar N Khan
Journal:  Int J Spine Surg       Date:  2018-08-03

5.  Effect of Myelopathy on Early Clinical Improvement After Cervical Disc Replacement: A Study of a Local Patient Cohort and a Large National Cohort.

Authors:  Andre M Samuel; Harold G Moore; Avani S Vaishnav; Steven McAnany; Todd Albert; Sravisht Iyer; Yoshihiro Katsuura; Catherine Himo Gang; Sheeraz A Qureshi
Journal:  Neurospine       Date:  2019-09-30

6.  Comorbidities associated with cervical spine degenerative disc disease.

Authors:  Mark J Lambrechts; Kyle Maryan; Wyatt Whitman; Tzu-Chuan Yen; Jinpu Li; Emily V Leary; James L Cook; Theodore J Choma
Journal:  J Orthop       Date:  2021-07-16
  6 in total

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