| Literature DB >> 26913086 |
Aswani Srinivas Mareddy1, Dharshan Rangaswamy1, Mahesha Vankalakunti2, Ravindra Prabhu Attur1, Shankar Prasad Nagaraju1, Neeraja Koti3.
Abstract
Hepatitis B virus (HBV) infection presenting as crescentic glomerulonephritis in the absence of cryoglobulinemia is an extremely rare phenomenon. We report a case of a 44-year-old male with HBV infection, who underwent kidney biopsy for rapidly progressive renal failure and nephrotic range proteinuria. Histopathological evaluation of the kidney biopsy was consistent with immune complex mediated crescentic membranoproliferative glomerulonephritis (MPGN). The patient achieved complete renal and virological remission with steroids, plasmapheresis and antiviral therapy. This case report summarises the importance of early initiation of immunosuppression and plasmapheresis under antiviral coverage for improved clinical outcomes.Entities:
Keywords: Hepatitis B Virus; MPGN; crescentic glomerulonephritis; crescentic membranoproliferative glomerulonephritis
Year: 2016 PMID: 26913086 PMCID: PMC4748015 DOI: 10.4066/AMJ.2015.2568
Source DB: PubMed Journal: Australas Med J ISSN: 1836-1935