Literature DB >> 26912759

Diagnosis of Clostridium difficile Infections in Children.

Stella Antonara1, Amy L Leber2.   

Abstract

The detection and diagnosis of Clostridium difficile infection in pediatric populations have some unique considerations in comparison to testing in adults. The testing methodologies, including toxigenic culture, cell cytotoxicity, antigen detection, and, more recently, molecular testing, are the same in all age groups. However, limited data exist on the specific performance characteristics in children. In this review, we focus on the challenges of testing in pediatric populations and assess the available data on test performance in these populations. Additionally, a review of the existing guidance for testing is provided.
Copyright © 2016, American Society for Microbiology. All Rights Reserved.

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Year:  2016        PMID： 26912759      PMCID： PMC4879289          DOI： 10.1128/JCM.03014-15

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


  46 in total

Review 1.  Guidelines for diagnosis, treatment, and prevention of Clostridium difficile infections.

Authors:  Christina M Surawicz; Lawrence J Brandt; David G Binion; Ashwin N Ananthakrishnan; Scott R Curry; Peter H Gilligan; Lynne V McFarland; Mark Mellow; Brian S Zuckerbraun
Journal:  Am J Gastroenterol       Date:  2013-02-26       Impact factor: 10.864

Review 2.  Pitfalls in Diagnosis of Pediatric Clostridium difficile Infection.

Authors:  Julia S Sammons; Philip Toltzis
Journal:  Infect Dis Clin North Am       Date:  2015-07-16       Impact factor: 5.982

3.  Gastrointestinal pathogens detected by multiplex nucleic acid amplification testing in stools of pediatric patients and patients returning from the tropics.

Authors:  C Beckmann; U Heininger; H Marti; H H Hirsch
Journal:  Infection       Date:  2014-12       Impact factor: 3.553

4.  Clostridium difficile infection diagnosis in a paediatric population: comparison of methodologies.

Authors:  J Hart; P Putsathit; D R Knight; L Sammels; T V Riley; A Keil
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2014-04-30       Impact factor: 3.267

5.  Clostridium difficile infection in hospitalized children in the United States.

Authors:  Cade M Nylund; Anthony Goudie; Jose M Garza; Gerry Fairbrother; Mitchell B Cohen
Journal:  Arch Pediatr Adolesc Med       Date:  2011-01-03

Review 6.  Asymptomatic colonization by Clostridium difficile in infants: implications for disease in later life.

Authors:  Sushrut Jangi; J Thomas Lamont
Journal:  J Pediatr Gastroenterol Nutr       Date:  2010-07       Impact factor: 2.839

7.  Clostridium difficile testing algorithms using glutamate dehydrogenase antigen and C. difficile toxin enzyme immunoassays with C. difficile nucleic acid amplification testing increase diagnostic yield in a tertiary pediatric population.

Authors:  Kaede V Ota; Karin L McGowan
Journal:  J Clin Microbiol       Date:  2012-01-18       Impact factor: 5.948

8.  Clostridium difficile infection is associated with increased risk of death and prolonged hospitalization in children.

Authors:  Julia Shaklee Sammons; Russell Localio; Rui Xiao; Susan E Coffin; Theoklis Zaoutis
Journal:  Clin Infect Dis       Date:  2013-03-26       Impact factor: 9.079

9.  Immunoglobulin and non-immunoglobulin components of human milk inhibit Clostridium difficile toxin A-receptor binding.

Authors:  R D Rolfe; W Song
Journal:  J Med Microbiol       Date:  1995-01       Impact factor: 2.472

10.  Novel risk factors for recurrent Clostridium difficile infection in children.

Authors:  Maribeth R Nicholson; Isaac P Thomsen; James C Slaughter; C Buddy Creech; Kathryn M Edwards
Journal:  J Pediatr Gastroenterol Nutr       Date:  2015-01       Impact factor: 2.839
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  10 in total

1.  Pediatric Clinical Microbiology: It's the Little Things.

Authors:  Chris D Doern; James J Dunn; Alexander J McAdam
Journal:  J Clin Microbiol       Date:  2016-04-13       Impact factor: 5.948

2.  An evaluation of toxigenic Clostridioides difficile positivity as a patient outcome metric of antimicrobial stewardship in Saudi Arabia.

Authors:  Christopher A Okeahialam; Ali A Rabaan; Albert Bolhuis
Journal:  J Infect Prev       Date:  2021-06-22

3.  Recurrent community-acquired Clostridium(Clostridioides)difficile infection in Serbianchildren.

Authors:  Stojanovic Predrag; Ed J Kuijper; Stojanović Nikola; Karuna E W Vendrik; Radulović Niko
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2019-11-12       Impact factor: 3.267

4.  Rapid change of fecal microbiome and disappearance of Clostridium difficile in a colonized infant after transition from breast milk to cow milk.

Authors:  Manli Y Davis; Husen Zhang; Lera E Brannan; Robert J Carman; James H Boone
Journal:  Microbiome       Date:  2016-10-07       Impact factor: 14.650

Review 5.  Clostridium difficile Infection in Special High-Risk Populations.

Authors:  Alberto Cózar-Llistó; Antonio Ramos-Martinez; Javier Cobo
Journal:  Infect Dis Ther       Date:  2016-08-11

6.  A retrospective study of community-acquired Clostridium difficile infection in southwest China.

Authors:  Feng Liao; Wenge Li; Wenpeng Gu; Wenzhu Zhang; Xiaoshu Liu; Xiaoqing Fu; Wen Xu; Yuan Wu; Jinxing Lu
Journal:  Sci Rep       Date:  2018-03-05       Impact factor: 4.379

7.  Incidence, course, and outcome of Clostridium difficile infection in children with hematological malignancies or undergoing hematopoietic stem cell transplantation.

Authors:  Małgorzata Salamonowicz; T Ociepa; J Frączkiewicz; A Szmydki-Baran; M Matysiak; K Czyżewski; M Wysocki; P Gałązka; P Zalas-Więcek; N Irga-Jaworska; E Drożyńska; O Zając-Spychała; J Wachowiak; O Gryniewicz-Kwiatkowska; A Czajńska-Deptuła; B Dembowska-Bagińska; L Chełmecka-Wiktorczyk; W Balwierz; M Bartnik; K Zielezińska; T Urasiński; R Tomaszewska; T Szczepański; M Płonowski; M Krawczuk-Rybak; F Pierlejewski; W Młynarski; Z Gamrot-Pyka; M Woszczyk; Z Małas; W Badowska; A Urbanek-Dądela; G Karolczyk; W Stolpa; G Sobol-Milejska; A Zaucha-Prażmo; J Kowalczyk; J Goździk; E Gorczyńska; K Jermakow; A Król; A Chybicka; M Ussowicz; K Kałwak; J Styczyński
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2018-07-05       Impact factor: 3.267

Review 8.  Expanding Existing Antimicrobial Stewardship Programs in Pediatrics: What Comes Next.

Authors:  Matthew P Kronman; Ritu Banerjee; Jennifer Duchon; Jeffrey S Gerber; Michael D Green; Adam L Hersh; David Hyun; Holly Maples; Colleen B Nash; Sarah Parker; Sameer J Patel; Lisa Saiman; Pranita D Tamma; Jason G Newland
Journal:  J Pediatric Infect Dis Soc       Date:  2018-08-17       Impact factor: 3.164

Review 9.  Gut Dysbiosis and Clostridioides difficile Infection in Neonates and Adults.

Authors:  Iulia-Magdalena Vasilescu; Mariana-Carmen Chifiriuc; Gratiela Gradisteanu Pircalabioru; Roxana Filip; Alexandra Bolocan; Veronica Lazăr; Lia-Mara Diţu; Coralia Bleotu
Journal:  Front Microbiol       Date:  2022-01-20       Impact factor: 5.640

Review 10.  New Developments in Rapid Diagnostic Testing for Children.

Authors:  Mark D Gonzalez; Erin McElvania
Journal:  Infect Dis Clin North Am       Date:  2017-12-18       Impact factor: 5.982
  10 in total

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