Literature DB >> 26912685

HEART DISEASE. Throttling back the heart's molecular motor.

David M Warshaw1.   

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Year:  2016        PMID： 26912685      PMCID： PMC4847938          DOI： 10.1126/science.aaf1636

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


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  15 in total

1.  A small-molecule inhibitor of sarcomere contractility suppresses hypertrophic cardiomyopathy in mice.

Authors:  Eric M Green; Hiroko Wakimoto; Robert L Anderson; Marc J Evanchik; Joshua M Gorham; Brooke C Harrison; Marcus Henze; Raja Kawas; Johan D Oslob; Hector M Rodriguez; Yonghong Song; William Wan; Leslie A Leinwand; James A Spudich; Robert S McDowell; J G Seidman; Christine E Seidman
Journal:  Science       Date:  2016-02-05       Impact factor: 47.728

2.  A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation.

Authors:  A A Geisterfer-Lowrance; S Kass; G Tanigawa; H P Vosberg; W McKenna; C E Seidman; J G Seidman
Journal:  Cell       Date:  1990-09-07       Impact factor: 41.582

3.  Cardiac myosin activation: a potential therapeutic approach for systolic heart failure.

Authors:  Fady I Malik; James J Hartman; Kathleen A Elias; Bradley P Morgan; Hector Rodriguez; Katjusa Brejc; Robert L Anderson; Sandra H Sueoka; Kenneth H Lee; Jeffrey T Finer; Roman Sakowicz; Ramesh Baliga; David R Cox; Marc Garard; Guillermo Godinez; Raja Kawas; Erica Kraynack; David Lenzi; Pu Ping Lu; Alexander Muci; Congrong Niu; Xiangping Qian; Daniel W Pierce; Maria Pokrovskii; Ion Suehiro; Sheila Sylvester; Todd Tochimoto; Corey Valdez; Wenyue Wang; Tatsuo Katori; David A Kass; You-Tang Shen; Stephen F Vatner; David J Morgans
Journal:  Science       Date:  2011-03-18       Impact factor: 47.728

Review 4.  Understanding cardiomyopathy phenotypes based on the functional impact of mutations in the myosin motor.

Authors:  Jeffrey R Moore; Leslie Leinwand; David M Warshaw
Journal:  Circ Res       Date:  2012-07-20       Impact factor: 17.367

Review 5.  In the thick of it: HCM-causing mutations in myosin binding proteins of the thick filament.

Authors:  Samantha P Harris; Ross G Lyons; Kristina L Bezold
Journal:  Circ Res       Date:  2011-03-18       Impact factor: 17.367

6.  Differences in clinical expression of hypertrophic cardiomyopathy associated with two distinct mutations in the beta-myosin heavy chain gene. A 908Leu----Val mutation and a 403Arg----Gln mutation.

Authors:  N D Epstein; G M Cohn; F Cyran; L Fananapazir
Journal:  Circulation       Date:  1992-08       Impact factor: 29.690

Review 7.  Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion.

Authors:  Houman Ashrafian; Charles Redwood; Edward Blair; Hugh Watkins
Journal:  Trends Genet       Date:  2003-05       Impact factor: 11.639

8.  Single-molecule mechanics of R403Q cardiac myosin isolated from the mouse model of familial hypertrophic cardiomyopathy.

Authors:  M J Tyska; E Hayes; M Giewat; C E Seidman; J G Seidman; D M Warshaw
Journal:  Circ Res       Date:  2000-04-14       Impact factor: 17.367

9.  Molecular mechanics of cardiac myosin-binding protein C in native thick filaments.

Authors:  M J Previs; S Beck Previs; J Gulick; J Robbins; D M Warshaw
Journal:  Science       Date:  2012-08-23       Impact factor: 47.728

10.  Skeletal muscle expression and abnormal function of beta-myosin in hypertrophic cardiomyopathy.

Authors:  G Cuda; L Fananapazir; W S Zhu; J R Sellers; N D Epstein
Journal:  J Clin Invest       Date:  1993-06       Impact factor: 14.808
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