Literature DB >> 26910573

Brugada Phenocopy Induced by Electrolyte Disorder: A Transient Electrocardiographic Sign.

Aysel Hunuk1, Burak Hunuk2, Ozlem Kusken1, Ozge Ecmel Onur1.   

Abstract

Brugada syndrome (BrS) is an important cause of sudden cardiac death (SCD) with well-defined ST-segment elevation patterns on V1 -V3 . Observation of BrS-Type-electrocardiogram (ECG) patterns in medical conditions without true BrS is called "Brugada Phenocopy" (BrP). We present a case of 61-year-old male patient with hyperkalemia, hyponatremia, and BrS-Type-1 ECG pattern in the setting of acute postrenal failure. He was denying any syncope or family history of SCD. With normalization of electrolyte levels, BrS-Type-1-ECG resolved. Electrolyte disturbances are one of the most common reasons of BrP. Being aware of BrPs and differentiating from an unmasked BrS-ECG pattern could prevent patients from lethal consequences and unnecessary treatments.
© 2016 Wiley Periodicals, Inc.

Entities:  

Keywords:  Brugada phenocopy; Brugada syndrome; acute renal failure; hyperkalemia; hyponatremia

Mesh:

Year:  2016        PMID: 26910573      PMCID: PMC6931746          DOI: 10.1111/anec.12350

Source DB:  PubMed          Journal:  Ann Noninvasive Electrocardiol        ISSN: 1082-720X            Impact factor:   1.468


  11 in total

Review 1.  The Brugada syndrome: diagnostic criteria and cellular mechanisms.

Authors:  C Antzelevitch
Journal:  Eur Heart J       Date:  2001-03       Impact factor: 29.983

2.  The hyperkalemic Brugada sign.

Authors:  Laszlo Littmann; Michael H Monroe; Lee Taylor; William D Brearley
Journal:  J Electrocardiol       Date:  2007-01       Impact factor: 1.438

3.  Concomitant-acquired Long QT and Brugada syndromes associated with indapamide-induced hypokalemia and hyponatremia.

Authors:  Ngai-Shing Mok; Chak-Kwan Tong; Ho-Chuen Yuen
Journal:  Pacing Clin Electrophysiol       Date:  2008-06       Impact factor: 1.976

Review 4.  Brugada phenocopy: new terminology and proposed classification.

Authors:  Adrian Baranchuk; Timothy Nguyen; Min Hyung Ryu; Francisco Femenía; Wojciech Zareba; Arthur A M Wilde; Wataru Shimizu; Pedro Brugada; Andrés R Pérez-Riera
Journal:  Ann Noninvasive Electrocardiol       Date:  2012-08-13       Impact factor: 1.468

5.  Brugada phenocopy: morphological classification and importance of provocative testing.

Authors:  Byron Gottschalk; Daniel D Anselm; Adrian Baranchuk
Journal:  Ann Noninvasive Electrocardiol       Date:  2014-09-09       Impact factor: 1.468

Review 6.  Brugada syndrome: report of the second consensus conference: endorsed by the Heart Rhythm Society and the European Heart Rhythm Association.

Authors:  Charles Antzelevitch; Pedro Brugada; Martin Borggrefe; Josep Brugada; Ramon Brugada; Domenico Corrado; Ihor Gussak; Herve LeMarec; Koonlawee Nademanee; Andres Ricardo Perez Riera; Wataru Shimizu; Eric Schulze-Bahr; Hanno Tan; Arthur Wilde
Journal:  Circulation       Date:  2005-01-17       Impact factor: 29.690

Review 7.  Propofol infusion syndrome and Brugada syndrome electrocardiographic phenocopy.

Authors:  Andrés Ricardo Pérez Riera; Augusto Hiroshi Uchida; Edgardo Schapachnik; Sergio Dubner; Celso Ferreira Filho; Celso Ferreira
Journal:  Cardiol J       Date:  2010       Impact factor: 2.737

8.  The pathophysiological mechanism underlying Brugada syndrome: depolarization versus repolarization.

Authors:  Arthur A M Wilde; Pieter G Postema; José M Di Diego; Sami Viskin; Hiroshi Morita; Jeffrey M Fish; Charles Antzelevitch
Journal:  J Mol Cell Cardiol       Date:  2010-07-24       Impact factor: 5.000

9.  Cellular basis for the Brugada syndrome and other mechanisms of arrhythmogenesis associated with ST-segment elevation.

Authors:  G X Yan; C Antzelevitch
Journal:  Circulation       Date:  1999-10-12       Impact factor: 29.690

10.  Current electrocardiographic criteria for diagnosis of Brugada pattern: a consensus report.

Authors:  Antonio Bayés de Luna; Josep Brugada; Adrian Baranchuk; Martin Borggrefe; Guenter Breithardt; Diego Goldwasser; Pier Lambiase; Andrés Pérez Riera; Javier Garcia-Niebla; Carlos Pastore; Giuseppe Oreto; William McKenna; Wojciech Zareba; Ramon Brugada; Pedro Brugada
Journal:  J Electrocardiol       Date:  2012-09       Impact factor: 1.438

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  2 in total

1.  Brugada syndrome, Brugada phenocopy or none?

Authors:  Umut Kocabas; Can Hasdemir; Esra Kaya; Cuneyt Turkoglu; Adrian Baranchuk
Journal:  Ann Noninvasive Electrocardiol       Date:  2017-06-13       Impact factor: 1.468

2.  Brugada phenocopy secondary to hyperkalemia and hyponatremia in primary adrenal insufficiency.

Authors:  Olga Amusina; Sandeep Mehta; Michael E Nelson
Journal:  J Am Coll Emerg Physicians Open       Date:  2022-08-10
  2 in total

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