Literature DB >> 26909718

Metastatic Prostate Cancer With Restored Hormone-Response After Radioligand Therapy With 177Lu-PSMA-617.

Carl Diedrich Schlenkhoff1, Eberhard Knüpfer, Markus Essler, Hojjat Ahmadzadehfar.   

Abstract

An 80-year-old patient with castrate-resistant prostate cancer presented to our department for PSMA imaging because of a rising prostate-specific antigen (PSA) level. The tumor was diagnosed in 2004. GnRh analog was the only treatment the patient received. Two cycles of Lu-PSMA-617 were performed with a 2-month interval in between. Ten months after finishing with 2 cycles of Lu-PSMA therapy, we noticed a continuous falling PSA level and a decreasing tumor spread in the PET/CT imaging just under the hormone therapy.

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Year:  2016        PMID: 26909718     DOI: 10.1097/RLU.0000000000001200

Source DB:  PubMed          Journal:  Clin Nucl Med        ISSN: 0363-9762            Impact factor:   7.794


  8 in total

1.  Overall survival and response pattern of castration-resistant metastatic prostate cancer to multiple cycles of radioligand therapy using [177Lu]Lu-PSMA-617.

Authors:  Hojjat Ahmadzadehfar; Simone Wegen; Anna Yordanova; Rolf Fimmers; Stefan Kürpig; Elisabeth Eppard; Xiao Wei; Carl Schlenkhoff; Stefan Hauser; Markus Essler
Journal:  Eur J Nucl Med Mol Imaging       Date:  2017-05-09       Impact factor: 9.236

Review 2.  PSMA PET and Radionuclide Therapy in Prostate Cancer.

Authors:  Kirsten Bouchelouche; Baris Turkbey; Peter L Choyke
Journal:  Semin Nucl Med       Date:  2016-09-03       Impact factor: 4.446

3.  Predictors of overall survival in metastatic castration-resistant prostate cancer patients receiving [177Lu]Lu-PSMA-617 radioligand therapy.

Authors:  Hojjat Ahmadzadehfar; Stephan Schlolaut; Rolf Fimmers; Anna Yordanova; Stefan Hirzebruch; Carl Schlenkhoff; Florian C Gaertner; Zool Hilmi Awang; Stefan Hauser; Markus Essler
Journal:  Oncotarget       Date:  2017-10-07

4.  External radiation exposure, excretion, and effective half-life in 177Lu-PSMA-targeted therapies.

Authors:  J Kurth; B J Krause; S M Schwarzenböck; L Stegger; M Schäfers; K Rahbar
Journal:  EJNMMI Res       Date:  2018-04-12       Impact factor: 3.138

5.  Uptake of PSMA-ligands in normal tissues is dependent on tumor load in patients with prostate cancer.

Authors:  Florian C Gaertner; Khalil Halabi; Hojjat Ahmadzadehfar; Stefan Kürpig; Elisabeth Eppard; Charalambos Kotsikopoulos; Nikolaos Liakos; Ralph A Bundschuh; Holger Strunk; Markus Essler
Journal:  Oncotarget       Date:  2017-07-06

6.  Repeated PSMA-targeting radioligand therapy of metastatic prostate cancer with 131I-MIP-1095.

Authors:  Ali Afshar-Oromieh; Uwe Haberkorn; Christian Zechmann; Thomas Armor; Walter Mier; Fabian Spohn; Nils Debus; Tim Holland-Letz; John Babich; Clemens Kratochwil
Journal:  Eur J Nucl Med Mol Imaging       Date:  2017-03-09       Impact factor: 9.236

Review 7.  PSMA-PET based radiotherapy: a review of initial experiences, survey on current practice and future perspectives.

Authors:  Sebastian Zschaeck; Fabian Lohaus; Marcus Beck; Gregor Habl; Stephanie Kroeze; Constantinos Zamboglou; Stefan Alexander Koerber; Jürgen Debus; Tobias Hölscher; Peter Wust; Ute Ganswindt; Alexander D J Baur; Klaus Zöphel; Nikola Cihoric; Matthias Guckenberger; Stephanie E Combs; Anca Ligia Grosu; Pirus Ghadjar; Claus Belka
Journal:  Radiat Oncol       Date:  2018-05-11       Impact factor: 3.481

Review 8.  Neuroendocrine Differentiation of Prostate Cancer-An Intriguing Example of Tumor Evolution at Play.

Authors:  Girijesh Kumar Patel; Natasha Chugh; Manisha Tripathi
Journal:  Cancers (Basel)       Date:  2019-09-20       Impact factor: 6.639

  8 in total

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