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Literature DB >> 26906681

Birth and upgrowth of the Hox topological domains during evolution.

Abstract

The recently discovered chromatin compartments called topologically associating domains (TADs) are essential for the three-dimensional organization of regulatory interactions driving gene expression. A new study documents the emergence of a TAD flanking the amphioxus Hox cluster, prefiguring the vertebrate anterior Hox TAD and preceding the appearance of the concurring posterior Hox TAD.

Entities: Species

Mesh：

Substances：
Homeodomain Proteins

Year: 2016 PMID： 26906681 DOI： 10.1038/ng.3514

Source DB: PubMed Journal: Nat Genet ISSN： 1061-4036 Impact factor: 38.330

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References

13 in total

1. A regulatory archipelago controls Hox genes transcription in digits.

Authors: Thomas Montavon; Natalia Soshnikova; Bénédicte Mascrez; Elisabeth Joye; Laurie Thevenet; Erik Splinter; Wouter de Laat; François Spitz; Denis Duboule
Journal: Cell Date: 2011-11-23 Impact factor: 41.582

Review 2. Topology of mammalian developmental enhancers and their regulatory landscapes.

Authors: Wouter de Laat; Denis Duboule
Journal: Nature Date: 2013-10-24 Impact factor: 49.962

3. Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci.

Authors: Nicolas Lonfat; Thomas Montavon; Fabrice Darbellay; Sandra Gitto; Denis Duboule
Journal: Science Date: 2014-11-21 Impact factor: 47.728

Review 4. The architecture of gene expression: integrating dispersed cis-regulatory modules into coherent regulatory domains.

Authors: Wibke Schwarzer; François Spitz
Journal: Curr Opin Genet Dev Date: 2014-06-05 Impact factor: 5.578

Birth and upgrowth of the Hox topological domains during evolution.

1. A regulatory archipelago controls Hox genes transcription in digits.

Review 2. Topology of mammalian developmental enhancers and their regulatory landscapes.

3. Convergent evolution of complex regulatory landscapes and pleiotropy at Hox loci.

Review 4. The architecture of gene expression: integrating dispersed cis-regulatory modules into coherent regulatory domains.

5. A switch between topological domains underlies HoxD genes collinearity in mouse limbs.

6. Topological domains in mammalian genomes identified by analysis of chromatin interactions.

7. Comparative Hi-C reveals that CTCF underlies evolution of chromosomal domain architecture.

8. Cohesin-mediated interactions organize chromosomal domain architecture.

9. Conservation and divergence of regulatory strategies at Hox Loci and the origin of tetrapod digits.

10. A Hox regulatory network of hindbrain segmentation is conserved to the base of vertebrates.