Literature DB >> 26906610

New Momentum for the Field of Oligonucleotide Therapeutics.

Annemieke Aartsma-Rus1.   

Abstract

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Year:  2016        PMID： 26906610      PMCID： PMC4817824          DOI： 10.1038/mt.2016.14

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   11.454


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  14 in total

1.  The Evolving Druggability and Developability Space: Chemically Modified New Modalities and Emerging Small Molecules.

Authors:  Wenzhan Yang; Prajakta Gadgil; Venkata R Krishnamurthy; Margaret Landis; Pankajini Mallick; Dipal Patel; Phenil J Patel; Darren L Reid; Manuel Sanchez-Felix
Journal:  AAPS J       Date:  2020-01-03       Impact factor: 4.009

2.  Modeling Splicing Variants Amenable to Antisense Therapy by Use of CRISPR-Cas9-Based Gene Editing in HepG2 Cells.

Authors:  Arístides López-Márquez; Ainhoa Martínez-Pizarro; Belén Pérez; Eva Richard; Lourdes R Desviat
Journal:  Methods Mol Biol       Date:  2022

3.  Effect of PEG Architecture on the Hybridization Thermodynamics and Protein Accessibility of PEGylated Oligonucleotides.

Authors:  Fei Jia; Xueguang Lu; Xuyu Tan; Dali Wang; Xueyan Cao; Ke Zhang
Journal:  Angew Chem Int Ed Engl       Date:  2016-12-29       Impact factor: 16.823

4.  2'-O-(N-(Aminoethyl)carbamoyl)methyl Modification Allows for Lower Phosphorothioate Content in Splice-Switching Oligonucleotides with Retained Activity.

Authors:  Dmytro Honcharenko; Cristina S J Rocha; Karin E Lundin; Jyotirmoy Maity; Stefan Milton; Ulf Tedebark; Merita Murtola; Malgorzata Honcharenko; Andis Slaitas; C I Edvard Smith; Rula Zain; Roger Strömberg
Journal:  Nucleic Acid Ther       Date:  2022-03-02       Impact factor: 4.244

Review 5.  The Use of Tricyclo-DNA Oligomers for the Treatment of Genetic Disorders.

Authors:  Philippine Aupy; Lucía Echevarría; Karima Relizani; Aurélie Goyenvalle
Journal:  Biomedicines       Date:  2017-12-22

6.  Hydrogel-Assisted Antisense LNA Gapmer Delivery for In Situ Gene Silencing in Spinal Cord Injury.

Authors:  Pedro M D Moreno; Ana R Ferreira; Daniela Salvador; Maria T Rodrigues; Marília Torrado; Eva D Carvalho; Ulf Tedebark; Mónica M Sousa; Isabel F Amaral; Jesper Wengel; Ana P Pêgo
Journal:  Mol Ther Nucleic Acids       Date:  2018-03-20       Impact factor: 8.886

7.  Intronic PAH gene mutations cause a splicing defect by a novel mechanism involving U1snRNP binding downstream of the 5' splice site.

Authors:  Ainhoa Martínez-Pizarro; Maja Dembic; Belén Pérez; Brage S Andresen; Lourdes R Desviat
Journal:  PLoS Genet       Date:  2018-04-23       Impact factor: 5.917

8.  Assessment of the Drug Interaction Potential of Unconjugated and GalNAc3-Conjugated 2'-MOE-ASOs.

Authors:  Colby S Shemesh; Rosie Z Yu; Mark S Warren; Michael Liu; Mirza Jahic; Brandon Nichols; Noah Post; Song Lin; Daniel A Norris; Eunju Hurh; Jane Huang; Tanya Watanabe; Scott P Henry; Yanfeng Wang
Journal:  Mol Ther Nucleic Acids       Date:  2017-08-30

Review 9.  Delivery is key: lessons learnt from developing splice-switching antisense therapies.

Authors:  Caroline Godfrey; Lourdes R Desviat; Bård Smedsrød; France Piétri-Rouxel; Michela A Denti; Petra Disterer; Stéphanie Lorain; Gisela Nogales-Gadea; Valentina Sardone; Rayan Anwar; Samir El Andaloussi; Taavi Lehto; Bernard Khoo; Camilla Brolin; Willeke Mc van Roon-Mom; Aurélie Goyenvalle; Annemieke Aartsma-Rus; Virginia Arechavala-Gomeza
Journal:  EMBO Mol Med       Date:  2017-05       Impact factor: 12.137

10.  In vitro inhibition of porcine reproductive and respiratory syndrome virus replication by short antisense oligonucleotides with locked nucleic acid modification.

Authors:  Lingyun Zhu; Junlong Bi; Longlong Zheng; Qian Zhao; Xianghua Shu; Gang Guo; Jia Liu; Guishu Yang; Jianping Liu; Gefen Yin
Journal:  BMC Vet Res       Date:  2018-03-26       Impact factor: 2.741
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