| Literature DB >> 26905059 |
Wim Van Rossom1, Daniel J Asby1, Ali Tavassoli1, Philip A Gale1.
Abstract
A new class of anion transporter named 'perenosins' consisting of a pyrrole linked through an imine to either an indole, benzimidazole or indazole is reported. The indole containing members of the perenosin family function as effective transmembrane Cl(-)/NO3(-) antiporters and HCl cotransporters in a manner similar to the prodigiosenes. The compounds reduce the viability of MDA-MB-231 and MCF-7.Entities:
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Year: 2016 PMID： 26905059 DOI： 10.1039/c6ob00002a
Source DB: PubMed Journal: Org Biomol Chem ISSN： 1477-0520 Impact factor: 3.876