Literature DB >> 26904522

Treatment of unstable osteochondritis dissecans in adults with autogenous osteochondral grafts (Mosaicplasty): long-term results.

Mario Ronga1, Placido Stissi1, Giuseppe LA Barbera1, Marco Valoroso1, Gloria Angeretti2, Eugenio Genovese3, Paolo Cherubino1.   

Abstract

PURPOSE: the unstable osteochondritis dissecans (OCD-type II and III according to the ICRS classification) of the knee largher than > 2.5 cm(2) in adults are uncommon lesions and there is no consensus on how to treat them. Medium-term studies have reported good results using autogenous osteochondral plugs (mosaicplasty). The aim of this study is to analyze the long-term results of this technique for the treatment of unstable OCD in a selected group of adult patients.
METHODS: four patients with OCD at either one of the femoral condyles were included in this prospective study. The average age was 21.2 years (range, 18-24 years). The OCD lesions were classified as type II in three patients and type III in one patient and the average size was 3.8 cm(2) (range, 2.55-5.1 cm(2)). The lesions were treated in situ with a variable number of autogenous osteochondral plugs (Ø 4.5 mm(2)). The Modified Cincinnati, Lysholm II and Tegner scores were used for clinical and functional evaluation. Magnetic resonance arthrography (MRA) was performed before surgery and at 2, 5 and 10 years after surgery. A modified MOCART score was used to evaluate MRA findings.
RESULTS: the average follow-up duration was ten years and 6 months (range, 10-11 years). No complications occurred. At the final follow-up, all scores (clinical, functional and MOCART) improved. In all but one of the patients MRA showed complete osteochondral repair.
CONCLUSIONS: the fixation of large and unstable OCD lesions with mosaicplasty may be a good option for treating type II or III OCD lesions in adults. The advantages of this technique include stable fixation, promotion of blood supply to the base of the OCD fragment, and grafting of autologous cancellous bone that stimulates healing with preservation of the articular surface. LEVEL OF EVIDENCE: Level IV, therapeutic case series.

Entities:  

Keywords:  MR arthrography; adults; osteochondral graft; osteochondritis dissecans

Year:  2016        PMID: 26904522      PMCID: PMC4739536          DOI: 10.11138/jts/2015.3.4.173

Source DB:  PubMed          Journal:  Joints        ISSN: 2512-9090


  22 in total

Review 1.  Management of osteochondritis dissecans of the knee: current concepts review.

Authors:  Mininder S Kocher; Rachael Tucker; Theodore J Ganley; John M Flynn
Journal:  Am J Sports Med       Date:  2006-07       Impact factor: 6.202

2.  Update on advanced surgical techniques in the treatment of traumatic focal articular cartilage lesions in the knee.

Authors:  Nicholas A Sgaglione; Anthony Miniaci; Scott D Gillogly; Thomas R Carter
Journal:  Arthroscopy       Date:  2002-02       Impact factor: 4.772

3.  A prospective randomized clinical study of mosaic osteochondral autologous transplantation versus microfracture for the treatment of osteochondral defects in the knee joint in young athletes.

Authors:  Rimtautas Gudas; Romas J Kalesinskas; Vytautas Kimtys; Edgaras Stankevicius; Vytautas Toliusis; Giedrius Bernotavicius; Alfredas Smailys
Journal:  Arthroscopy       Date:  2005-09       Impact factor: 4.772

4.  Rating systems in the evaluation of knee ligament injuries.

Authors:  Y Tegner; J Lysholm
Journal:  Clin Orthop Relat Res       Date:  1985-09       Impact factor: 4.176

5.  The incidence of osteochondritis dissecans in the condyles of the femur.

Authors:  B Lindén
Journal:  Acta Orthop Scand       Date:  1976-12

Review 6.  The basic science of the subchondral bone.

Authors:  Henning Madry; C Niek van Dijk; Magdalena Mueller-Gerbl
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2010-01-30       Impact factor: 4.342

7.  Osteochondritis dissecans of the knee: arthroscopic compression screw fixation.

Authors:  L L Johnson; G Uitvlugt; M D Austin; D A Detrisac; C Johnson
Journal:  Arthroscopy       Date:  1990       Impact factor: 4.772

8.  Tibial cortical bone peg fixation in osteochondritis dissecans of the knee.

Authors:  J A Slough; A M Noto; T L Schmidt
Journal:  Clin Orthop Relat Res       Date:  1991-06       Impact factor: 4.176

9.  Manual punch versus power harvesting of osteochondral grafts.

Authors:  Peter J Evans; Anthony Miniaci; Mark B Hurtig
Journal:  Arthroscopy       Date:  2004-03       Impact factor: 4.772

10.  Osteochondritis dissecans and osteochondral fragments managed by Herbert compression screw fixation.

Authors:  N L Thomson
Journal:  Clin Orthop Relat Res       Date:  1987-11       Impact factor: 4.176

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  4 in total

1.  Knee osteochondritis dissecans-treatment technical aspects.

Authors:  Mats Brittberg
Journal:  J Orthop       Date:  2022-08-11

2.  Osteochondritis Dissecans of the Knee: Short-Term Outcomes of a Hybrid Technique to Restore a Partially Salvageable Progeny Fragment.

Authors:  Heath P Melugin; Vishal S Desai; Bruce A Levy; Yoshinari Tanaka; Shuji Horibe; Norimasa Nakamura; Aaron J Krych
Journal:  Cartilage       Date:  2018-08-24       Impact factor: 4.634

Review 3.  [Cartilage repair of the knee joint].

Authors:  B Rath; J Eschweiler; M Betsch; G Gruber
Journal:  Orthopade       Date:  2017-11       Impact factor: 1.087

4.  Matrix-assisted chondrocyte transplantation with bone grafting for knee osteochondritis dissecans: stable results at 12 years.

Authors:  Luca Andriolo; Alessandro Di Martino; Sante Alessandro Altamura; Angelo Boffa; Alberto Poggi; Maurizio Busacca; Stefano Zaffagnini; Giuseppe Filardo
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2020-08-18       Impact factor: 4.342

  4 in total

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