Literature DB >> 26902587

Cellular processes underlying cerebral cavernous malformations: Autophagy as another point of view.

Saverio Marchi1, Saverio Francesco Retta2, Paolo Pinton1.   

Abstract

A growing amount of evidence indicates that autophagy plays a pivotal role in a plethora of human pathological conditions. We have recently broadened the list of the so-called autophagy-related diseases, describing the involvement of defective autophagy in the pathogenesis of cerebral cavernous malformations.

Entities:  

Keywords:  CCM; MTOR; ROS; autophagy; endothelial-to-mesenchymal transition (EndMt); pharmacological therapy

Mesh：

Year:  2016        PMID： 26902587      PMCID： PMC4836013          DOI： 10.1080/15548627.2015.1125073

Source DB:  PubMed          Journal:  Autophagy        ISSN： 1554-8627            Impact factor:   16.016


  7 in total

Review 1.  Oxidative stress and inflammation in cerebral cavernous malformation disease pathogenesis: Two sides of the same coin.

Authors:  Saverio Francesco Retta; Angela J Glading
Journal:  Int J Biochem Cell Biol       Date:  2016-09-14       Impact factor: 5.085

2.  KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease.

Authors:  Cinzia Antognelli; Eliana Trapani; Simona Delle Monache; Andrea Perrelli; Martina Daga; Stefania Pizzimenti; Giuseppina Barrera; Paola Cassoni; Adriano Angelucci; Lorenza Trabalzini; Vincenzo Nicola Talesa; Luca Goitre; Saverio Francesco Retta
Journal:  Free Radic Biol Med       Date:  2017-11-21       Impact factor: 7.376

Review 3.  Vitamin D Deficiency and the Risk of Cerebrovascular Disease.

Authors:  Hyun Ah Kim; Andrea Perrelli; Alberto Ragni; Francesca Retta; T Michael De Silva; Christopher G Sobey; Saverio Francesco Retta
Journal:  Antioxidants (Basel)       Date:  2020-04-17

Review 4.  Dicarbonyl Stress and S-Glutathionylation in Cerebrovascular Diseases: A Focus on Cerebral Cavernous Malformations.

Authors:  Cinzia Antognelli; Andrea Perrelli; Tatiana Armeni; Vincenzo Nicola Talesa; Saverio Francesco Retta
Journal:  Antioxidants (Basel)       Date:  2020-02-01

5.  KRIT1 Deficiency Promotes Aortic Endothelial Dysfunction.

Authors:  Francesco Vieceli Dalla Sega; Raffaella Mastrocola; Giorgio Aquila; Francesca Fortini; Claudia Fornelli; Alessia Zotta; Alessia S Cento; Andrea Perrelli; Enrica Boda; Antonio Pannuti; Saverio Marchi; Paolo Pinton; Roberto Ferrari; Paola Rizzo; Saverio Francesco Retta
Journal:  Int J Mol Sci       Date:  2019-10-05       Impact factor: 5.923

6.  Next-Generation Sequencing Advances the Genetic Diagnosis of Cerebral Cavernous Malformation (CCM).

Authors:  Valerio Benedetti; Rosalia Canzoneri; Andrea Perrelli; Carlo Arduino; Andrea Zonta; Alfredo Brusco; Saverio Francesco Retta
Journal:  Antioxidants (Basel)       Date:  2022-06-29

7.  Heterozygous Loss of KRIT1 in Mice Affects Metabolic Functions of the Liver, Promoting Hepatic Oxidative and Glycative Stress.

Authors:  Raffaella Mastrocola; Eleonora Aimaretti; Gustavo Ferreira Alves; Alessia Sofia Cento; Claudia Fornelli; Federica Dal Bello; Chiara Ferraris; Luca Goitre; Andrea Perrelli; Saverio Francesco Retta
Journal:  Int J Mol Sci       Date:  2022-09-22       Impact factor: 6.208
  7 in total

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