Literature DB >> 26902288

Keeping homologous recombination in check.

Kasper Fugger1, Stephen C West1.   

Abstract

Pathway choice is a critical event in the repair of DNA double-strand breaks. In a recent paper published in Nature, Orthwein et al. define a mechanism by which homologous recombination is controlled in G1 cells to favor non-homologous end joining.

Mesh：

Year:  2016        PMID： 26902288      PMCID： PMC4822126          DOI： 10.1038/cr.2016.25

Source DB:  PubMed          Journal:  Cell Res        ISSN： 1001-0602            Impact factor:   25.617


  10 in total

Review 1.  Double-strand break end resection and repair pathway choice.

Authors:  Lorraine S Symington; Jean Gautier
Journal:  Annu Rev Genet       Date:  2011-09-12       Impact factor: 16.830

2.  BRCA1 accelerates CtIP-mediated DNA-end resection.

Authors:  Andrés Cruz-García; Ana López-Saavedra; Pablo Huertas
Journal:  Cell Rep       Date:  2014-10-09       Impact factor: 9.423

3.  A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.

Authors:  Cristina Escribano-Díaz; Alexandre Orthwein; Amélie Fradet-Turcotte; Mengtan Xing; Jordan T F Young; Ján Tkáč; Michael A Cook; Adam P Rosebrock; Meagan Munro; Marella D Canny; Dongyi Xu; Daniel Durocher
Journal:  Mol Cell       Date:  2013-01-17       Impact factor: 17.970

4.  53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.

Authors:  Samuel F Bunting; Elsa Callén; Nancy Wong; Hua-Tang Chen; Federica Polato; Amanda Gunn; Anne Bothmer; Niklas Feldhahn; Oscar Fernandez-Capetillo; Liu Cao; Xiaoling Xu; Chu-Xia Deng; Toren Finkel; Michel Nussenzweig; Jeremy M Stark; André Nussenzweig
Journal:  Cell       Date:  2010-04-01       Impact factor: 41.582

Review 5.  Therapeutic genome editing: prospects and challenges.

Authors:  David Benjamin Turitz Cox; Randall Jeffrey Platt; Feng Zhang
Journal:  Nat Med       Date:  2015-02       Impact factor: 53.440

6.  Purified human BRCA2 stimulates RAD51-mediated recombination.

Authors:  Ryan B Jensen; Aura Carreira; Stephen C Kowalczykowski
Journal:  Nature       Date:  2010-10-07       Impact factor: 49.962

7.  A mechanism for the suppression of homologous recombination in G1 cells.

Authors:  Alexandre Orthwein; Sylvie M Noordermeer; Marcus D Wilson; Sébastien Landry; Radoslav I Enchev; Alana Sherker; Meagan Munro; Jordan Pinder; Jayme Salsman; Graham Dellaire; Bing Xia; Matthias Peter; Daniel Durocher
Journal:  Nature       Date:  2015-12-09       Impact factor: 49.962

8.  REV7 counteracts DNA double-strand break resection and affects PARP inhibition.

Authors:  J Ross Chapman; Inger Brandsma; Guotai Xu; Jingsong Yuan; Martin Mistrik; Peter Bouwman; Jirina Bartkova; Ewa Gogola; Daniël Warmerdam; Marco Barazas; Janneke E Jaspers; Kenji Watanabe; Mark Pieterse; Ariena Kersbergen; Wendy Sol; Patrick H N Celie; Philip C Schouten; Bram van den Broek; Ahmed Salman; Marja Nieuwland; Iris de Rink; Jorma de Ronde; Kees Jalink; Simon J Boulton; Junjie Chen; Dik C van Gent; Jiri Bartek; Jos Jonkers; Piet Borst; Sven Rottenberg
Journal:  Nature       Date:  2015-03-23       Impact factor: 49.962

9.  Human CtIP mediates cell cycle control of DNA end resection and double strand break repair.

Authors:  Pablo Huertas; Stephen P Jackson
Journal:  J Biol Chem       Date:  2009-02-07       Impact factor: 5.157

10.  Structure and mechanism of action of the BRCA2 breast cancer tumor suppressor.

Authors:  Taha Shahid; Joanna Soroka; Eric Kong; Laurent Malivert; Michael J McIlwraith; Tillman Pape; Stephen C West; Xiaodong Zhang
Journal:  Nat Struct Mol Biol       Date:  2014-10-05       Impact factor: 15.369
  10 in total
  2 in total

Review 1.  DNA Damage and Repair Deficiency in ALS/FTD-Associated Neurodegeneration: From Molecular Mechanisms to Therapeutic Implication.

Authors:  Haibo Wang; Manohar Kodavati; Gavin W Britz; Muralidhar L Hegde
Journal:  Front Mol Neurosci       Date:  2021-12-16       Impact factor: 5.639

2.  AOP report: Development of an adverse outcome pathway for oxidative DNA damage leading to mutations and chromosomal aberrations.

Authors:  Eunnara Cho; Ashley Allemang; Marc Audebert; Vinita Chauhan; Stephen Dertinger; Giel Hendriks; Mirjam Luijten; Francesco Marchetti; Sheroy Minocherhomji; Stefan Pfuhler; Daniel J Roberts; Kristina Trenz; Carole L Yauk
Journal:  Environ Mol Mutagen       Date:  2022-05-03       Impact factor: 3.579
  2 in total

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