Literature DB >> 26901531

The novel tumor suppressor AIRAPL regulates IGF1R proteostasis.

Fernando G Osorio1, José M P Freije1, Carlos López-Otín1.   

Abstract

Entities:  

Keywords:  aging; cancer; insulin-IGF-1 signaling; myeloproliferative neoplasm; proteostasis

Mesh：

Substances：

Year:  2016        PMID： 26901531      PMCID： PMC4889228          DOI： 10.1080/15384101.2016.1151725

Source DB:  PubMed          Journal:  Cell Cycle        ISSN： 1551-4005            Impact factor:   4.534


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  7 in total

1.  Targeting a regulator of protein homeostasis in myeloproliferative neoplasms.

Authors:  Lindsay M LaFave; Ross L Levine
Journal:  Nat Med       Date:  2016-01       Impact factor: 53.440

2.  Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signaling.

Authors:  Fernando G Osorio; Clara Soria-Valles; Olaya Santiago-Fernández; Teresa Bernal; María Mittelbrunn; Enrique Colado; Francisco Rodríguez; Elena Bonzon-Kulichenko; Jesús Vázquez; Montserrat Porta-de-la-Riva; Julián Cerón; Antonio Fueyo; Juan Li; Anthony R Green; José M P Freije; Carlos López-Otín
Journal:  Nat Med       Date:  2015-12-21       Impact factor: 53.440

3.  Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans.

Authors:  Chi Yun; Ariel Stanhill; Yun Yang; Yuhong Zhang; Cole M Haynes; Chong-Feng Xu; Thomas A Neubert; Adam Mor; Mark R Philips; David Ron
Journal:  Proc Natl Acad Sci U S A       Date:  2008-05-08       Impact factor: 11.205

Review 4.  Insulin and insulin-like growth factor signalling in neoplasia.

Authors:  Michael Pollak
Journal:  Nat Rev Cancer       Date:  2008-12       Impact factor: 60.716

Review 5.  The hallmarks of aging.

Authors:  Carlos López-Otín; Maria A Blasco; Linda Partridge; Manuel Serrano; Guido Kroemer
Journal:  Cell       Date:  2013-06-06       Impact factor: 41.582

6.  Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells.

Authors:  Brad Dykstra; Sandra Olthof; Jaring Schreuder; Martha Ritsema; Gerald de Haan
Journal:  J Exp Med       Date:  2011-11-21       Impact factor: 14.307

7.  Proteasomal degradation of preemptive quality control (pQC) substrates is mediated by an AIRAPL-p97 complex.

Authors:  Ilana Braunstein; Lolita Zach; Susanne Allan; Kai-Uwe Kalies; Ariel Stanhill
Journal:  Mol Biol Cell       Date:  2015-09-02       Impact factor: 4.138
  7 in total

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