| Literature DB >> 26900363 |
Fatma Keklik1, Melda Cömert Özkan2, Gizem Kocabaş Yenipazar3, Banu Yaman4, Güray Saydam2, Fahri Şahin2.
Abstract
Toxic epidermal necrolysis (TEN) is a disease which is characterized by fever and desquamation of the skin and mucosal membranes. It is usually related with drugs, especially aromatic anticonvulsants which are recognized as the most common cause of this disorder. Cranial irradiation may act as a precipitating factor along with anticonvulsants for the development of TEN. We report a 28-year-old patient with central nervous system (CNS) relapsed non-Hodgkin lymphoma (NHL) who developed TEN after cranial radiotherapy and concurrent phenytoin treatment.Entities:
Keywords: Fenitoin; Radiotherapy; Toxic epidermal necrolysis
Year: 2015 PMID: 26900363 PMCID: PMC4716394 DOI: 10.1016/j.rpor.2015.09.002
Source DB: PubMed Journal: Rep Pract Oncol Radiother ISSN: 1507-1367