Literature DB >> 26900362

Vemurafenib and concomitant stereotactic radiation for the treatment of melanoma with spinal metastases: A case report.

Dinu Stefan1, Hosni Popotte1, Andreea Raluca Stefan2, Audrey Tesniere2, Aurélie Tomaszewski1, Paul Lesueur1, Jean-Louis Habrand1, Laurence Verneuil2.   

Abstract

A 56-year-old man with BRAFV600E melanoma and spinal metastases treated with vemurafenib and stereotactic radiation showed a partial response without neurological, skin or mucosal toxicity, 8 months after completion of this combination. This case suggests that stereotactic radiation spares normal tissues and might be safer than conventional fractionated radiation with vemurafenib.

Entities:  

Keywords:  Melanoma metastasis; Stereotactic radiation; Vemurafenib

Year:  2015        PMID： 26900362      PMCID： PMC4716399          DOI： 10.1016/j.rpor.2015.07.005

Source DB:  PubMed          Journal:  Rep Pract Oncol Radiother        ISSN： 1507-1367


  13 in total

1.  Radiosurgery for spinal metastases: clinical experience in 500 cases from a single institution.

Authors:  Peter C Gerszten; Steven A Burton; Cihat Ozhasoglu; William C Welch
Journal:  Spine (Phila Pa 1976)       Date:  2007-01-15       Impact factor: 3.468

2.  Severe liver and skin toxicity after radiation and vemurafenib in metastatic melanoma.

Authors:  Christopher J Anker; Antoni Ribas; Allie H Grossmann; Xinjian Chen; Krishna K Narra; Wallace Akerley; Robert H I Andtbacka; Robert Dirk Noyes; Dennis C Shrieve; Kenneth F Grossmann
Journal:  J Clin Oncol       Date:  2013-05-06       Impact factor: 44.544

3.  Cancer incidence and mortality in France over the period 1978-2000.

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Journal:  Rev Epidemiol Sante Publique       Date:  2003-02       Impact factor: 1.019

4.  Inhibition of mutated, activated BRAF in metastatic melanoma.

Authors:  Keith T Flaherty; Igor Puzanov; Kevin B Kim; Antoni Ribas; Grant A McArthur; Jeffrey A Sosman; Peter J O'Dwyer; Richard J Lee; Joseph F Grippo; Keith Nolop; Paul B Chapman
Journal:  N Engl J Med       Date:  2010-08-26       Impact factor: 91.245

5.  Malignant melanoma and central nervous system metastases: incidence, diagnosis, treatment and survival.

Authors:  M H Amer; M Al-Sarraf; L H Baker; V K Vaitkevicius
Journal:  Cancer       Date:  1978-08       Impact factor: 6.860

6.  Metastatic pattern of malignant melanoma. A study of 216 autopsy cases.

Authors:  J K Patel; M S Didolkar; J W Pickren; R H Moore
Journal:  Am J Surg       Date:  1978-06       Impact factor: 2.565

7.  Incidence of brain metastases in a cohort of patients with carcinoma of the breast, colon, kidney, and lung and melanoma.

Authors:  Leo J Schouten; Joost Rutten; Hans A M Huveneers; Albert Twijnstra
Journal:  Cancer       Date:  2002-05-15       Impact factor: 6.860

8.  Incidence proportions of brain metastases in patients diagnosed (1973 to 2001) in the Metropolitan Detroit Cancer Surveillance System.

Authors:  Jill S Barnholtz-Sloan; Andrew E Sloan; Faith G Davis; Fawn D Vigneau; Ping Lai; Raymond E Sawaya
Journal:  J Clin Oncol       Date:  2004-07-15       Impact factor: 44.544

9.  Cancer incidence and mortality in France over the period 1980-2005.

Authors:  A Belot; P Grosclaude; N Bossard; E Jougla; E Benhamou; P Delafosse; A-V Guizard; F Molinié; A Danzon; S Bara; A-M Bouvier; B Trétarre; F Binder-Foucard; M Colonna; L Daubisse; G Hédelin; G Launoy; N Le Stang; M Maynadié; A Monnereau; X Troussard; J Faivre; A Collignon; I Janoray; P Arveux; A Buemi; N Raverdy; C Schvartz; M Bovet; L Chérié-Challine; J Estève; L Remontet; M Velten
Journal:  Rev Epidemiol Sante Publique       Date:  2008-06-10       Impact factor: 1.019

10.  Spinal metastases: the obvious, the occult, and the impostors.

Authors:  D A Wong; V L Fornasier; I MacNab
Journal:  Spine (Phila Pa 1976)       Date:  1990-01       Impact factor: 3.468
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  1 in total

Review 1.  Radiation myelopathy following stereotactic body radiation therapy for spine metastases.

Authors:  Wee Loon Ong; Shun Wong; Hany Soliman; Sten Myrehaug; Chia-Lin Tseng; Jay Detsky; Zain Husain; Pejman Maralani; Lijun Ma; Simon S Lo; Arjun Sahgal
Journal:  J Neurooncol       Date:  2022-06-23       Impact factor: 4.506
  1 in total

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