Literature DB >> 26899607

A Long-term Survivor after Congenital Acute Myeloid Leukemia with t(8 ; 16)(p11 ; p13).

Takae Hanada1, Kiichiro Kanamitsu, Kosuke Chayama, Takako Miyamura, Yui Kanazawa, Michiko Muraoka, Kana Washio, Masahide Imada, Misao Kageyama, Akihito Takeuchi, Kei Tamai, Megumi Oda, Akira Shimada.   

Abstract

The treatment of patients with congenital leukemia is difficult and often results in a poor prognosis. We present here the case of a female child with congenital acute myeloid leukemia (AML) with t(8 ; 16) (p11 ; p13) who received chemotherapy and survived for more than 10 years without relapse. A novel MOZ-CBP chimera was found in her diagnostic sample. Although adult AML patients with MOZ-CBP have mainly been reported as having therapy-related AML and showed poor prognoses, the present case supports the idea that AML with MOZ-CBP in the pediatric population might show better prognoses.

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Year:  2016        PMID: 26899607     DOI: 10.18926/AMO/54001

Source DB:  PubMed          Journal:  Acta Med Okayama        ISSN: 0386-300X            Impact factor:   0.892


  2 in total

1.  Congenital Acute Myeloid Leukaemia with Pseudo-Chediak-Higashi Like Granules: A Case Report.

Authors:  Vandana Puri; Sandip Barman; Pooja Sharma; Meera Sikka
Journal:  J Clin Diagn Res       Date:  2016-11-01

2.  Panel-based next-generation sequencing facilitates the characterization of childhood acute myeloid leukemia in clinical settings.

Authors:  Hisashi Ishida; Akihiro Iguchi; Michinori Aoe; Ritsuo Nishiuchi; Takehiro Matsubara; Dai Keino; Masashi Sanada; Akira Shimada
Journal:  Biomed Rep       Date:  2020-08-28
  2 in total

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