Literature DB >> 26897633

Dental Stigmata of Congenital Syphilis: A Historic Review With Present Day Relevance.

Eranga H Nissanka-Jayasuriya1, Edward W Odell2, Carina Phillips3.   

Abstract

Syphilis was the first sexually transmitted disease to be diagnosed in childhood. Most developed countries controlled syphilis effectively after the 1950s and congenital syphilis became rare. Since the late 1990s there has been a resurgence of syphilis in developed and developing countries and the WHO estimates that at least half a million infants die of congenital syphilis every year. The earliest reference to the dental manifestations of congenital syphilis was by Sir Jonathan Hutchinson, Assistant Surgeon at The London Hospital in 1861. Three main dental defects are described in congenital syphilis; Hutchinson's incisors, Moon's molars or bud molars, and Fournier's molars or mulberry molars. Although many physicians, dentists, and pathologists in developed countries will be aware of the dental features of syphilis, most will never have seen a case or made the diagnosis. The purpose of this article is to review some of the history of congenital syphilis, remind healthcare professionals of the features, and bring to their attention that the changes are still prevalent and that milder cases can be mistaken for other causes of hypoplasia.

Entities:  

Keywords:  Congenital syphilis; Hutchinson’s incisors; Moon’s molars; Mulberry molars

Mesh:

Year:  2016        PMID: 26897633      PMCID: PMC4972761          DOI: 10.1007/s12105-016-0703-z

Source DB:  PubMed          Journal:  Head Neck Pathol        ISSN: 1936-055X


  14 in total

1.  Congenital syphilis in the past: slaves at Newton Plantation, Barbados, West Indies.

Authors:  K P Jacobi; D C Cook; R S Corruccini; J S Handler
Journal:  Am J Phys Anthropol       Date:  1992-10       Impact factor: 2.868

2.  The Oslo study of untreated syphilis; an epidemiologic investigation of the natural course of the syphilitic infection based upon a re-study of the Boeck-Bruusgaard material.

Authors:  T Gjestland
Journal:  Acta Derm Venereol Suppl (Stockh)       Date:  1955

Review 3.  Sexually transmitted diseases in children: introduction.

Authors:  S Estreich; G E Forster
Journal:  Genitourin Med       Date:  1992-02

4.  Congenital syphilis in Switzerland: gone, forgotten, on the return.

Authors:  Patrick M Meyer Sauteur; Johannes Trück; Philipp P Bosshard; Maren Tomaske; Francisca Morán Cadenas; Stephan Lautenschlager; Philippe Goetschel
Journal:  Swiss Med Wkly       Date:  2012-01-11       Impact factor: 2.193

5.  Dental changes in congenital syphilis. Relationship to other syphilitic stigmata.

Authors:  T PUTKONEN
Journal:  Acta Derm Venereol       Date:  1962       Impact factor: 4.437

6.  Tooth Buds and Jaws in Patients with Congenital Syphilis: Correlation between Distribution of Treponema pallidum and Tissue Reaction.

Authors:  W H Bauer
Journal:  Am J Pathol       Date:  1944-03       Impact factor: 4.307

7.  Characterisation of developmentally hypomineralised human enamel.

Authors:  Felicity A Crombie; David J Manton; Joseph E A Palamara; Ilya Zalizniak; Nathan J Cochrane; Eric C Reynolds
Journal:  J Dent       Date:  2013-05-15       Impact factor: 4.379

8.  Manifestations of late congenital syphilis. An analysis of 271 patients.

Authors:  N J Fiumara; S Lessell
Journal:  Arch Dermatol       Date:  1970-07

Review 9.  Untreated maternal syphilis and adverse outcomes of pregnancy: a systematic review and meta-analysis.

Authors:  Gabriela B Gomez; Mary L Kamb; Lori M Newman; Jennifer Mark; Nathalie Broutet; Sarah J Hawkes
Journal:  Bull World Health Organ       Date:  2013-01-17       Impact factor: 9.408

Review 10.  Oral manifestations of syphilis.

Authors:  Jair Carneiro Leão; Luiz Alcino Gueiros; Stephen R Porter
Journal:  Clinics (Sao Paulo)       Date:  2006-04-25       Impact factor: 2.365

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  6 in total

1.  Dental Traits of Congenital Syphilis Revisited in Dental Outpatient Department (OPD).

Authors:  Thorakkal Shamim; Prabha Surendran Renjini
Journal:  Head Neck Pathol       Date:  2017-03-24

2.  Syphilis in pregnancy and infant outcomes in Manitoba.

Authors:  Alison Lopez; Santina J Lee; Jared Bullard
Journal:  Paediatr Child Health       Date:  2022-03-21       Impact factor: 2.600

3.  Genetic Evidence Supporting the Role of the Calcium Channel, CACNA1S, in Tooth Cusp and Root Patterning.

Authors:  Virginie Laugel-Haushalter; Supawich Morkmued; Corinne Stoetzel; Véronique Geoffroy; Jean Muller; Anne Boland; Jean-François Deleuze; Kirsley Chennen; Waranuch Pitiphat; Hélène Dollfus; Karen Niederreither; Agnès Bloch-Zupan; Patimaporn Pungchanchaikul
Journal:  Front Physiol       Date:  2018-09-26       Impact factor: 4.566

4.  Historic Treponema pallidum genomes from Colonial Mexico retrieved from archaeological remains.

Authors:  Verena J Schuenemann; Aditya Kumar Lankapalli; Rodrigo Barquera; Elizabeth A Nelson; Diana Iraíz Hernández; Víctor Acuña Alonzo; Kirsten I Bos; Lourdes Márquez Morfín; Alexander Herbig; Johannes Krause
Journal:  PLoS Negl Trop Dis       Date:  2018-06-21

5.  Oral Manifestations of Syphilis: Report of Four Cases.

Authors:  Suné Mulder van Staden; Carl de Villiers; Julandi Alwan; Mpho Moloi; Sibongile Mahlangu
Journal:  Pathogens       Date:  2022-05-24

Review 6.  Role of Maternal Infections and Inflammatory Responses on Craniofacial Development.

Authors:  Anjali Y Bhagirath; Manoj Reddy Medapati; Vivianne Cruz de Jesus; Sneha Yadav; Martha Hinton; Shyamala Dakshinamurti; Devi Atukorallaya
Journal:  Front Oral Health       Date:  2021-09-06
  6 in total

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