Literature DB >> 2689593

Nucleotide sequence of an OXA-2 beta-lactamase gene from the R-plasmid R1767 derived plasmid pBP11 and comparison to closely related resistance determinants found in R46 and Tn2603.

E J Nücken1, R B Henschke, F R Schmidt.   

Abstract

Plasmid pBP11 contains a sequence homologous to Tn21-like element Tn2410 encoding dihydropteroate synthetase and beta-lactamase OXA-2. The nucleotide sequence of a 1.5 kb segment of this region has been determined including the bla gene. It reveals strong sequence homology with the OXA-2 operon of plasmid R46. The implications of an additional 319 bp segment in pBP11 for the different evolution of R46/pKM101 and pBP11 are discussed.

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Year:  1989        PMID： 2689593     DOI： 10.1099/00221287-135-4-761

Source DB:  PubMed          Journal:  J Gen Microbiol        ISSN： 0022-1287


  8 in total

1.  Site-specific integration of genes into hot spots for recombination flanking aadA in Tn21 transposons.

Authors:  E J Nücken; R B Henschke; F R Schmidt
Journal:  Mol Gen Genet       Date:  1991-09

2.  Structural and functional characterization of tnpI, a recombinase locus in Tn21 and related beta-lactamase transposons.

Authors:  J Mercier; J Lachapelle; F Couture; M Lafond; G Vézina; M Boissinot; R C Levesque
Journal:  J Bacteriol       Date:  1990-07       Impact factor: 3.490

3.  Primary structure of OXA-3 and phylogeny of oxacillin-hydrolyzing class D beta-lactamases.

Authors:  F Sanschagrin; F Couture; R C Levesque
Journal:  Antimicrob Agents Chemother       Date:  1995-04       Impact factor: 5.191

4.  Transposon Tn5090 of plasmid R751, which carries an integron, is related to Tn7, Mu, and the retroelements.

Authors:  P Rådström; O Sköld; G Swedberg; J Flensburg; P H Roy; L Sundström
Journal:  J Bacteriol       Date:  1994-06       Impact factor: 3.490

5.  A novel dihydrofolate reductase cassette inserted in an integron borne on a Tn21-like element.

Authors:  E Heikkilä; M Skurnik; L Sundström; P Huovinen
Journal:  Antimicrob Agents Chemother       Date:  1993-06       Impact factor: 5.191

6.  Characterization of In0 of Pseudomonas aeruginosa plasmid pVS1, an ancestor of integrons of multiresistance plasmids and transposons of gram-negative bacteria.

Authors:  L Bissonnette; P H Roy
Journal:  J Bacteriol       Date:  1992-02       Impact factor: 3.490

7.  Genetic elements involved in Tn21 site-specific integration, a novel mechanism for the dissemination of antibiotic resistance genes.

Authors:  E Martinez; F de la Cruz
Journal:  EMBO J       Date:  1990-04       Impact factor: 11.598

8.  New nucleotide sequence data on the EMBL File Server.

Authors: 
Journal:  Nucleic Acids Res       Date:  1989-09-12       Impact factor: 16.971
  8 in total

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