Bieke Samijn1,2, Erik Van Laecke1,3, Catherine Renson3, Piet Hoebeke1,3, Frank Plasschaert4, Johan Vande Walle5, Christine Van den Broeck2. 1. Department of Uro-Gynaecology, Ghent University, Ghent, Belgium. 2. Department of Rehabilitation Sciences and Physiotherapy, Ghent University, Ghent, Belgium. 3. Department of Urology, Ghent University Hospital, Ghent, Belgium. 4. Department of Orthopaedic Surgery, Ghent University Hospital, Ghent, Belgium. 5. Department of Pediatric Nephrology and Rheumatology, Ghent University Hospital, Ghent, Belgium.
Abstract
AIMS: To systematically review the scientific literature addressing lower urinary tract symptoms (LUTS) and urodynamic findings in adults and children with Cerebral Palsy (CP). Prognostic factors were also investigated. METHODS: A systematic research was conducted on the electronic databases PubMed, Web of Science, and CINAHL. Only full text clinical trials which examined the prevalence of LUTS or urodynamic findings in children or adults with CP were eligible. LUTS and urodynamic findings, defined by the International Children's Continence Society, were extracted from the included studies. Pooled average of extracted data was calculated. Studies were scored on methodological and reporting quality using the Dutch Cochrane Checklist, EBRO guidelines, and the Strengthening the Reporting of Observational Studies in Epidemiology Statement (STROBE) checklist. RESULTS: Twenty-seven studies fulfilled selection criteria. Methodological and reporting quality were moderate to low. An average of 55.5% of subjects with CP experience one or more LUTS. Storage symptoms are more common than voiding symptoms due to the high prevalence of neurogenic detrusor overactivity. Patients with voiding symptoms and pelvic floor overactivity are more prone to progress to upper urinary tract dysfunction in adult life. Urodynamic evaluation can direct management. Negative prognostic factors are the spastic subtype with quadriplegic distribution, moderate to severe functional impairment (GMFCS III or higher) and severe cognitive impairment. CONCLUSION: The significant prevalence of LUTS, risk for deterioration, and the impact of urinary tract symptoms on quality of life and health status warrants the need for evaluation and treatment in further research. Neurourol. Urodynam. 36:541-549, 2017.
AIMS: To systematically review the scientific literature addressing lower urinary tract symptoms (LUTS) and urodynamic findings in adults and children with Cerebral Palsy (CP). Prognostic factors were also investigated. METHODS: A systematic research was conducted on the electronic databases PubMed, Web of Science, and CINAHL. Only full text clinical trials which examined the prevalence of LUTS or urodynamic findings in children or adults with CP were eligible. LUTS and urodynamic findings, defined by the International Children's Continence Society, were extracted from the included studies. Pooled average of extracted data was calculated. Studies were scored on methodological and reporting quality using the Dutch Cochrane Checklist, EBRO guidelines, and the Strengthening the Reporting of Observational Studies in Epidemiology Statement (STROBE) checklist. RESULTS: Twenty-seven studies fulfilled selection criteria. Methodological and reporting quality were moderate to low. An average of 55.5% of subjects with CP experience one or more LUTS. Storage symptoms are more common than voiding symptoms due to the high prevalence of neurogenic detrusor overactivity. Patients with voiding symptoms and pelvic floor overactivity are more prone to progress to upper urinary tract dysfunction in adult life. Urodynamic evaluation can direct management. Negative prognostic factors are the spastic subtype with quadriplegic distribution, moderate to severe functional impairment (GMFCS III or higher) and severe cognitive impairment. CONCLUSION: The significant prevalence of LUTS, risk for deterioration, and the impact of urinary tract symptoms on quality of life and health status warrants the need for evaluation and treatment in further research. Neurourol. Urodynam. 36:541-549, 2017.
Authors: Jay G Berry; Michael Glotzbecker; Jonathan Rodean; Izabela Leahy; Matt Hall; Lynne Ferrari Journal: Pediatrics Date: 2017-02-02 Impact factor: 7.124
Authors: Christopher S Ward; Teng-Wei Huang; José A Herrera; Rodney C Samaco; Meagan R Pitcher; Alan Herron; Steven A Skinner; Walter E Kaufmann; Daniel G Glaze; Alan K Percy; Jeffrey L Neul Journal: PLoS One Date: 2016-11-09 Impact factor: 3.240