Literature DB >> 26894170

The Release of Elements from the Base Metal Alloys in a Protein Containing Biologic Environments and Artificial Saliva - An Invitro Study.

Ashwin M Pangi1, Manoj Shetty2, D Krishna Prasad2, Hema Kanathila3.   

Abstract

INTRODUCTION: It has been reported that protein containing solutions can accelerate the release of elements from the base metal alloys. AIM: This study aims to determine whether the solution in which an alloy is submerged and the exposure time have any effect on the amount of release of elements from the Ni-Cr and Co-Cr alloys.
MATERIAL AND METHODS: A total of 126 specimens were made from the Ni-Cr alloy and 42 specimens were made from Co-Cr alloy in the form of 5mm diameter discs, 2mm in thickness. Dissolution experiments were carried out in Bovine Serum Albumin (BSA) and artificial saliva for a period of seven weeks and atomic absorption spectrophotometer was used for elemental analysis. STATISTICAL ANALYSIS: T-test was done to correlate the difference of elemental release from both BSA and artificial saliva. ANOVA test was done to compare the release at different time intervals and to compare the release of elements at different time intervals within a particular solution. TUKEY HSD test was done for comparison between the elements in a particular solution.
RESULTS: The results showed that the elemental release was seen in both the solutions with a significant increase of release in BSA. The release of elements from the Ni-Cr alloy showed the predominant release of Cr.
CONCLUSION: The protein containing solution showed maximum release of elements from Ni-Cr and Co-Cr alloys. The elements that released from the alloys never reached their threshold for toxic effects. Hence these alloys can be safely used in fabrication of metal restorations without any ill effects.

Entities:  

Keywords:  Biocompatibility; Bovine Serum Albumin; Co-Cr alloys; Corrosion; Ni-Cr alloys

Year:  2016        PMID: 26894170      PMCID: PMC4740698          DOI: 10.7860/JCDR/2016/15763.7058

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  16 in total

1.  Corrosion of nickel-based dental casting alloys.

Authors:  Christopher M Wylie; Richard M Shelton; Garry J P Fleming; Alison J Davenport
Journal:  Dent Mater       Date:  2006-09-01       Impact factor: 5.304

2.  Investigation of the threshold for allergic reactivity to chromium.

Authors:  D Basketter; L Horev; D Slodovnik; S Merimes; A Trattner; A Ingber
Journal:  Contact Dermatitis       Date:  2001-02       Impact factor: 6.600

3.  Elements released from dental casting alloys and their cytotoxic effects.

Authors:  Ahmad S al-Hiyasat; Omar M Bashabsheh; Homa Darmani
Journal:  Int J Prosthodont       Date:  2002 Sep-Oct       Impact factor: 1.681

4.  In vitro and in vivo corrosion evaluation of nickel-chromium- and copper-aluminum-based alloys.

Authors:  O F Benatti; W G Miranda; A Muench
Journal:  J Prosthet Dent       Date:  2000-09       Impact factor: 3.426

Review 5.  Metal release from dental biomaterials.

Authors:  D Brune
Journal:  Biomaterials       Date:  1986-05       Impact factor: 12.479

6.  Leaching of nickel, chromium, and beryllium ions from base metal alloy in an artificial oral environment.

Authors:  Y Tai; R De Long; R J Goodkind; W H Douglas
Journal:  J Prosthet Dent       Date:  1992-10       Impact factor: 3.426

Review 7.  Nickel, chromium and cobalt in consumer products: revisiting safe levels in the new millennium.

Authors:  David A Basketter; Gianni Angelini; Arieh Ingber; Petra S Kern; Torkil Menné
Journal:  Contact Dermatitis       Date:  2003-07       Impact factor: 6.600

8.  Elemental ion release from four different fixed prosthodontic materials.

Authors:  Waleed Elshahawy; Ikuya Watanabe; Mari Koike
Journal:  Dent Mater       Date:  2009-03-20       Impact factor: 5.304

9.  The release of elements from dental casting alloy into cell-culture medium and artificial saliva.

Authors:  Gülşen Can; Gül Akpınar; Ahmet Aydın
Journal:  Eur J Dent       Date:  2007-04

10.  Influence of shape and finishing on the corrosion of palladium-based dental alloys.

Authors:  Ana Milheiro; Joris Muris; Cornelis J Kleverlaan; Albert J Feilzer
Journal:  J Adv Prosthodont       Date:  2015-02-17       Impact factor: 1.904

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.