Literature DB >> 26894079

Cytodiagnosis of a Cutaneous Clear Cell Malignancy: Metastatic Renal Cell Carcinoma on Chin.

Anshu Singh1, Gyanendra Mohan2, Sunanda Chaturvedi3, Shakir Ali Khan4.   

Abstract

Clear cell type of renal cell carcinoma (RCC) is most common urological malignancy. Several diagnostic challenges arise when it presents as a cutaneous nodule, being an uncommon presentation. Fine needle aspiration cytology (FNAC) of a cutaneous nodule is crucial for distinguishing primary tumours from metastatic tumours because cutaneous metastases represent a terminal stage of illness. Due to considerable overlap of cytomorphological features determination of primary warrants need of detailed clinical history and close inspection of every cytological detail. We report here a case of cutaneous metastasis of RCC on chin in a patient 11 years after nephrectomy. Though there are reports of RCC metastases diagnosed on histology, there are fewer cytology case reports. Cytological differential diagnosis has been discussed for arriving at the final diagnosis in case of clear cell tumours. Early and accurate diagnosis is mandatory for optimal treatment. Cytodiagnosis of cutaneous metastasis of RCC is uncommon due to its low suspicion index in cutaneous nodules. More so, it presents late and an unusual sites due to its resemblance to common dermatological diseases.

Entities:  

Keywords:  Clear cell tumors; Cutaneous metastasis; Urological malignancy

Year:  2016        PMID: 26894079      PMCID: PMC4740607          DOI: 10.7860/JCDR/2016/15869.7100

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  9 in total

Review 1.  Clear cell melanoma: a cutaneous clear cell malignancy.

Authors:  Maria A Pletneva; Aleodor Andea; Nallasivam Palanisamy; Bryan L Betz; Shannon Carskadon; Min Wang; Rajiv M Patel; Douglas R Fullen; Paul W Harms
Journal:  Arch Pathol Lab Med       Date:  2014-10       Impact factor: 5.534

2.  Renal cell carcinoma with cutaneous metastases.

Authors:  Cathy Lim; Renee Chan; William Regan
Journal:  Australas J Dermatol       Date:  2005-08       Impact factor: 2.875

Review 3.  Clear cell entities of the head and neck: a selective review of clear cell tumors of the salivary glands.

Authors:  Nasser Said-Al-Naief; Michael J Klein
Journal:  Head Neck Pathol       Date:  2008-04-22

4.  Clear cell variant of squamous cell carcinoma of skin: A report of a case.

Authors:  Ahmed Oluwatoyin Lawal; Akinyele Olumuyiwa Adisa; Mofoluwaso A Olajide; Adeola Adenike Olusanya
Journal:  J Oral Maxillofac Pathol       Date:  2013-01

5.  Metastatic renal cell carcinoma presenting as a parotid tumor.

Authors:  Beatriz Patiño Seijas; Fernanda Lorenzo Franco; Roberto Martín Sastre; Augusto Alvarez García; José Luis López-Cedrún Cembranos
Journal:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod       Date:  2005-05

Review 6.  Renal cell carcinoma metastatic to the skin.

Authors:  S Koga; S Tsuda; M Nishikido; F Matsuya; Y Saito; H Kanetake
Journal:  Anticancer Res       Date:  2000 May-Jun       Impact factor: 2.480

7.  Renal cell carcinoma presenting with cutaneous metastasis: a case report.

Authors:  Nilufer Onak Kandemir; Figen Barut; Kıvanç Yılmaz; Husnu Tokgoz; Mubin Hosnuter; Sukru Oguz Ozdamar
Journal:  Case Rep Med       Date:  2010-08-02

8.  Cutaneous metastasis of bilateral renal cell carcinoma.

Authors:  Fariba Abbasi; Mansur Alizadeh; Farahnaz Noroozinia; Amin Moradi
Journal:  J Pak Med Assoc       Date:  2013-01       Impact factor: 0.781

9.  Renal cell carcinoma in India demonstrates early age of onset & a late stage of presentation.

Authors:  Shalini Agnihotri; Jatinder Kumar; Manoj Jain; Rakesh Kapoor; Anil Mandhani
Journal:  Indian J Med Res       Date:  2014-11       Impact factor: 2.375

  9 in total
  1 in total

1.  Cutaneous metastasis as the first sign of renal cell carcinoma - crossroad between literature analysis and own observations.

Authors:  Krzysztof Balawender; Rafał Przybyła; Stanisław Orkisz; Agata Wawrzyniak; Dariusz Boroñ; Beniamin O Grabarek
Journal:  Postepy Dermatol Alergol       Date:  2021-08-02       Impact factor: 1.664

  1 in total

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