Literature DB >> 26893701

Large moderately-differentiated ovarian Sertoli-Leydig cell tumor in a 13-year-old female: A case report.

Hui Zhang1, Jing Hao2, Chun-Yan Li1, Tao Li1, Yu-Lan Mu1.   

Abstract

Sertoli-Leydig cell tumor of the ovary, also known as androblastoma, is a rare neoplasm from the group of sex cord-stromal tumors of the ovary. The tumor accounts for <0.5% of all primary ovarian neoplasms. The clinical signs and symptoms of Sertoli-Leydig cell tumors can be associated with either hormonal production or the presence of a mass-occupying lesion. In the current study, a 13-year-old female was diagnosed with a stage Ic ovarian Sertoli-Leydig cell tumor following abdominal pain and distension. One month after a right oophorectomy, the follow-up magnetic resonance imaging scan was negative for residual or recurrent tumor. The overall 5-year survival rate for moderately-differentiated (grade 2) and poorly-differentiated (grade 3) Sertoli-Leydig cell tumors is 80%, and long-term follow-up is therefore highly advised in this patient.

Entities:  

Keywords:  Sertoli-Leydig cell tumor; hyperthyroidism; masculinization; ovary

Year:  2015        PMID: 26893701      PMCID: PMC4734072          DOI: 10.3892/ol.2015.3979

Source DB:  PubMed          Journal:  Oncol Lett        ISSN: 1792-1074            Impact factor:   2.967


  14 in total

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Authors:  Thomas Rio Frio; Amin Bahubeshi; Chryssa Kanellopoulou; Nancy Hamel; Marek Niedziela; Nelly Sabbaghian; Carly Pouchet; Lucy Gilbert; Paul K O'Brien; Kim Serfas; Peter Broderick; Richard S Houlston; Fabienne Lesueur; Elena Bonora; Stefan Muljo; R Neil Schimke; Dorothée Bouron-Dal Soglio; Jocelyne Arseneau; Kris Ann Schultz; John R Priest; Van-Hung Nguyen; H Rubén Harach; David M Livingston; William D Foulkes; Marc Tischkowitz
Journal:  JAMA       Date:  2011-01-05       Impact factor: 56.272

4.  Sertoli-Leydig cell tumors of the ovary: a Taiwanese Gynecologic Oncology Group study.

Authors:  Chia-Sui Weng; Min-Yu Chen; Tao-Yeuan Wang; Hsiao-Wen Tsai; Yao-Ching Hung; Ken-Jen Yu; Ying-Cheng Chiang; Hao Lin; Chien-Hsing Lu; Hung-Hsueh Chou
Journal:  Taiwan J Obstet Gynecol       Date:  2013-03       Impact factor: 1.705

5.  Embryonal rhabdomyosarcoma of the uterine cervix: a report of 14 cases and a discussion of its unusual clinicopathological associations.

Authors:  Louis P Dehner; Jason A Jarzembowski; D Ashley Hill
Journal:  Mod Pathol       Date:  2011-12-09       Impact factor: 7.842

6.  Sertoli-Leydig cell tumor of the ovary: analysis of a single institution database.

Authors:  Rani Akhil Bhat; Yong Kuei Lim; Yin Nin Chia; Kwai Lam Yam
Journal:  J Obstet Gynaecol Res       Date:  2012-06-13       Impact factor: 1.730

7.  Aromatase activity in human granulosa cells during follicular development and the modulation by follicle-stimulating hormone and insulin.

Authors:  V G Garzo; J H Dorrington
Journal:  Am J Obstet Gynecol       Date:  1984-03-01       Impact factor: 8.661

8.  DICER1 mutations in familial pleuropulmonary blastoma.

Authors:  D Ashley Hill; Jennifer Ivanovich; John R Priest; Christina A Gurnett; Louis P Dehner; David Desruisseau; Jason A Jarzembowski; Kathryn A Wikenheiser-Brokamp; Brian K Suarez; Alison J Whelan; Gretchen Williams; Dawn Bracamontes; Yoav Messinger; Paul J Goodfellow
Journal:  Science       Date:  2009-06-25       Impact factor: 47.728

Review 9.  Ovarian Sertoli-Leydig cell tumors. A clinicopathological analysis of 207 cases.

Authors:  R H Young; R E Scully
Journal:  Am J Surg Pathol       Date:  1985-08       Impact factor: 6.394

10.  Poorly differentiated ovarian sertoli-leydig cell tumor in a 16-year-old single woman: a case report and literature review.

Authors:  Ahmed Abu-Zaid; Ayman Azzam; Lama Abdulhamid Alghuneim; Mona Tarek Metawee; Tarek Amin; Turki Omar Al-Hussain
Journal:  Case Rep Obstet Gynecol       Date:  2013-06-25
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