| Literature DB >> 26893690 |
Zi-Yan Wang1, Kai Qiu1, Yi-Hui Ma2, Xiao-Tao Wang1, Jian-Ji Bao1, Zhi-Feng Zhang1, Xian-Zhi Liu1.
Abstract
Solitary fibrous tumors (SFTs) are uncommon, with the pleura as a site of predilection. Central nervous system SFTs, particularly intracranial SFTs, are extremely rare. The lesions are generally benign and localized, and surgery is the main therapeutic solution. The current study reports the cases of a patient who presented with right haunch pain, right leg weakness and paresthesias for several months, and a patient with a history of unexpected loss of consciousness. Magnetic resonance imaging revealed the presence of lesions, with a spindle cell morphology evident on pathological examination. The immunohistochemical examination demonstrated a strong immunoreaction for cluster of differentiation 34, which supported the diagnosis of an SFT. Following a near-total resection, the patients had a good neural prognosis. The present study also provides a literature review, discussing the imageological and pathological characteristics of SFT, and the diagnostic methods that aid in distinguishing the entity from other spindle-cell central nervous system tumors.Entities:
Keywords: central nervous system; extrapleural; solitary fibrous tumor
Year: 2015 PMID: 26893690 PMCID: PMC4734070 DOI: 10.3892/ol.2015.3985
Source DB: PubMed Journal: Oncol Lett ISSN: 1792-1074 Impact factor: 2.967