Literature DB >> 26893406

Paediatric procedural sedation using ketamine in a UK emergency department: a 7 year review of practice.

L R Kidd1, S C Lyons2, G Lloyd3.   

Abstract

BACKGROUND: Ketamine is growing in popularity for procedural sedation in the paediatric population, yet safety concerns remain. We performed a retrospective review of practice and outcomes of paediatric ketamine sedation using the World SIVA International Sedation Task Force reporting tool.
METHODS: A retrospective inspection of the dedicated emergency department electronic sedation database and subsequent note and sedation chart review was performed for all paediatric sedations throughout a 7 yr period from September 2006. All adverse events were stratified.
RESULTS: During the study period, procedural sedation was provided for a total of 243 children, of whom 215 were sedated with ketamine, most commonly for wound management (n=131). The median patient age was 4 yr (14 months to 15 yr), and 63.7% were male. Of the total, 76.7% were discharged home either directly (n=101) or after brief observation (n=64). One patient required subsequent general anaesthesia after a failed sedation with paradoxical agitation. Of the total, 9.8% of patients had an adverse event, the most severe risk stratification being 'minor risk'. All interventions were 'minimal risk'. There were no 'sentinel risk' outcomes.
CONCLUSIONS: These data support the ongoing use of ketamine for paediatric procedural sedation in the emergency department by emergency physicians. Relatively high resource requirements mean that ensuring adequate numbers of procedures may prove challenging.
© The Author 2016. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  adverse drug reaction reporting systems; anaesthetics, intravenous; emergency service, hospital; ketamine; sedation

Mesh:

Substances:

Year:  2016        PMID: 26893406     DOI: 10.1093/bja/aev555

Source DB:  PubMed          Journal:  Br J Anaesth        ISSN: 0007-0912            Impact factor:   9.166


  8 in total

1.  Risk Factors for Adverse Events in Emergency Department Procedural Sedation for Children.

Authors:  Maala Bhatt; David W Johnson; Jason Chan; Monica Taljaard; Nick Barrowman; Ken J Farion; Samina Ali; Suzanne Beno; Andrew Dixon; C Michelle McTimoney; Alexander Sasha Dubrovsky; Nadia Sourial; Mark G Roback
Journal:  JAMA Pediatr       Date:  2017-10-01       Impact factor: 16.193

Review 2.  Refractory symptoms in paediatric palliative care: can ketamine help?

Authors:  Franca Benini; Sabrina Congedi; Luca Giacomelli; Simonetta Papa; Aashni Shah; Gregorio Milani
Journal:  Drugs Context       Date:  2021-05-19

3.  Incidence and predictors of respiratory adverse events in children undergoing procedural sedation with intramuscular ketamine in a paediatric emergency department.

Authors:  Jia Le Lee; Lai Peng Tham
Journal:  Singapore Med J       Date:  2020-06-26       Impact factor: 3.331

4.  Use of ketamine sedation for the management of displaced paediatric forearm fractures.

Authors:  Anatole Vilhelm Wiik; Poonam Patel; Joanna Bovis; Adele Cowper; Philip Socrates Pastides; Alison Hulme; Stuart Evans; Charles Stewart
Journal:  World J Orthop       Date:  2018-03-18

5.  Safety and Efficacy of Procedural Sedation and Analgesia in Pediatric Oncology Patients.

Authors:  Saba Laila Aslam; Anwar Haque; Muhammad Tariq Jamil; Madiha Ariff; Saad Nasir
Journal:  Cureus       Date:  2020-03-28

6.  Multimodal imaging reveals transient liver metabolic disturbance and sinusoidal circulation obstruction after a single administration of ketamine/xylazine mixture.

Authors:  Fang-Hsin Chen; Ching-Fang Yu; Chung-Lin Yang; Yu-Chun Lin; Gigin Lin; Chun-Chieh Wang; Huang-Ping Yu; Jui Fang; Ning-Fang Chang; Ji-Hong Hong
Journal:  Sci Rep       Date:  2020-02-27       Impact factor: 4.379

7.  Results from the Adverse Event Sedation Reporting Tool: A Global Anthology of 7952 Records Derived from >160,000 Procedural Sedation Encounters.

Authors:  Keira P Mason; Mark G Roback; David Chrisp; Nicole Sturzenbaum; Lee Freeman; David Gozal; Firoz Vellani; David Cavanaugh; Steven M Green
Journal:  J Clin Med       Date:  2019-12-01       Impact factor: 4.241

8.  The Impact of a Dedicated Sedation Team on the Incidence of Complications in Pediatric Procedural Analgosedation.

Authors:  Sofia Apostolidou; Mirna Kintscher; Gerhard Schön; Chinedu Ulrich Ebenebe; Hans-Jürgen Bartz; Dominique Singer; Christian Zöllner; Katharina Röher
Journal:  Children (Basel)       Date:  2022-07-02
  8 in total

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