Literature DB >> 26892840

A peptide hydrogel derived from a fragment of human cardiac troponin C.

Luis M De Leon-Rodriguez1, Meder Kamalov2, Yacine Hemar2, Alok K Mitra1, Valeria Castelletto3, Daniel Hermida-Merino4, Ian W Hamley3, Margaret A Brimble1.   

Abstract

The human cardiac troponin C peptide fragment H-V(9)EQLTEEQKNEFKAAFDIFVLGA(31)-OH, which covers helix-A in the native protein, self-assembles into β-sheet fibrils in solution. These fibrils further entangle to give a hydrogel. This peptide may therefore serve as a template for development of novel biomaterials.

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Year:  2016        PMID: 26892840     DOI: 10.1039/c6cc00209a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Controlling self-assembly of diphenylalanine peptides at high pH using heterocyclic capping groups.

Authors:  Adam D Martin; Jonathan P Wojciechowski; Andrew B Robinson; Celine Heu; Christopher J Garvey; Julian Ratcliffe; Lynne J Waddington; James Gardiner; Pall Thordarson
Journal:  Sci Rep       Date:  2017-03-08       Impact factor: 4.379

2.  Ovalbumin Epitope SIINFEKL Self-Assembles into a Supramolecular Hydrogel.

Authors:  Meder Kamalov; Hanspeter Kählig; Christian Rentenberger; Alexander R M Müllner; Herwig Peterlik; Christian F W Becker
Journal:  Sci Rep       Date:  2019-02-25       Impact factor: 4.379

  2 in total

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