Literature DB >> 2689244

[The growth and morphophysiological study of the bushy tissue receptor in a nerve tissue culture].

O S Sotnikov, N I Chalisova, V N Maĭorov, G N Akoev, V P Goncharova.   

Abstract

The conditions for growing bush receptors on collagen substrate in presence of 2-4 ng/ml highly purified brain neurite stimulating protein were determined in the study of spinal ganglia cultures of 10-11-day chicken embryos. The degree of neurite branching and sinuosity and the distribution density of preterminals of cultured bush-like receptors are like those of chicken embryos' natural interoceptors. The ultrastructure of end receptor plates in culture resembles that of natural mechanoreceptor terminals. Cultural receptors are characterized by spontaneous electrophysiological activity. They respond to tactile irritation with bursts of discharges.

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Year:  1989        PMID: 2689244

Source DB:  PubMed          Journal:  Fiziol Zh SSSR Im I M Sechenova        ISSN: 0015-329X


  2 in total

Review 1.  Morphogenesis of neuron systems in tissue culture repeats evolutionarily simple nervous systems.

Authors:  O S Sotnikov
Journal:  Neurosci Behav Physiol       Date:  2000 Jul-Aug

2.  Effect of veratridine on the release of neurotrophic factors in nerve tissue cultures.

Authors:  G N Akoev; N I Chalisova; M I Lyudyno; D A Terent'ev; A V Romanyuk
Journal:  Neurosci Behav Physiol       Date:  1997 Nov-Dec
  2 in total

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