Literature DB >> 2689043

Clinical pharmacology and the choice between theory and empiricism.

L B Sheiner1.   

Abstract

Mesh：

Substances：

Year:  1989        PMID： 2689043     DOI： 10.1038/clpt.1989.195

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


× No keyword cloud information.
  10 in total

Review 1.  Interchangeability and predictive performance of empirical tolerance models.

Authors:  M Gårdmark; L Brynne; M Hammarlund-Udenaes; M O Karlsson
Journal:  Clin Pharmacokinet       Date:  1999-02       Impact factor: 6.447

2.  An example of optimal phase II design for exposure response modelling.

Authors:  Alan Maloney; Marloes Schaddelee; Jan Freijer; Walter Krauwinkel; Marcel van Gelderen; Philippe Jacqmin; Ulrika S H Simonsson
Journal:  J Pharmacokinet Pharmacodyn       Date:  2010-09-25       Impact factor: 2.745

Review 3.  Non-linear mixed effects modeling - from methodology and software development to driving implementation in drug development science.

Authors:  Goonaseelan Colin Pillai; France Mentré; Jean-Louis Steimer
Journal:  J Pharmacokinet Pharmacodyn       Date:  2005-11-07       Impact factor: 2.745

4.  Evaluation of agile designs in first-in-human (FIH) trials--a simulation study.

Authors:  Itay Perlstein; James A Bolognese; Rajesh Krishna; John A Wagner
Journal:  AAPS J       Date:  2009-09-16       Impact factor: 4.009

5.  The impact of arteriovenous concentration differences on pharmacodynamic parameter estimates.

Authors:  B Tuk; M Danhof; J W Mandema
Journal:  J Pharmacokinet Biopharm       Date:  1997-02

Review 6.  Pharmacokinetic-pharmacodynamic modelling in pre-clinical investigations: principles and perspectives.

Authors:  M Danhof; J W Mandema; A Hoogerkamp; R A Mathôt
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1993 Jan-Mar       Impact factor: 2.441

7.  Temporal linear mode complexity as a surrogate measure of the effect of remifentanil on the central nervous system in healthy volunteers.

Authors:  Byung-Moon Choi; Da-Huin Shin; Moon-Ho Noh; Young-Hac Kim; Yong-Bo Jeong; Soo-Han Lee; Eun-Kyung Lee; Gyu-Jeong Noh
Journal:  Br J Clin Pharmacol       Date:  2011-06       Impact factor: 4.335

8.  Methodologic aspects of a population pharmacodynamic model for cognitive effects in Alzheimer patients treated with tacrine.

Authors:  N H Holford; K E Peace
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-01       Impact factor: 11.205

9.  A physiologically based pharmacokinetic model for nicotine and cotinine in man.

Authors:  D E Robinson; N J Balter; S L Schwartz
Journal:  J Pharmacokinet Biopharm       Date:  1992-12

10.  Semiparametric analysis of non-steady-state pharmacodynamic data.

Authors:  D Verotta; L B Sheiner
Journal:  J Pharmacokinet Biopharm       Date:  1991-12
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.