PURPOSE OF REVIEW: Discuss the current status and obstacles that need to be overcome in the future to provide patient-centered care with left ventricular assist device (LVAD) therapy. RECENT FINDINGS: LVADs offer both longer survival and improvements in quality of life for carefully selected patients with inotrope-dependent heart failure. Yet, this technology does not come without significant risk of adverse effects and burdens. Recent observational data comparing LVAD with medical therapy in ambulatory, noninotrope-dependent patients with advanced heart failure suggest that survival may be similar and changes in quality of life may depend on baseline status. As both LVAD technology and medical therapy continue to evolve, there are many unanswered questions regarding the benefits, risks, and burdens of LVAD therapies in less severe heart failure populations. SUMMARY: Further research is needed to ensure the optimal delivery of LVAD therapy, including improved patient selection, implantation timing, device type, and decision support. VIDEO ABSTRACT.
PURPOSE OF REVIEW: Discuss the current status and obstacles that need to be overcome in the future to provide patient-centered care with left ventricular assist device (LVAD) therapy. RECENT FINDINGS:LVADs offer both longer survival and improvements in quality of life for carefully selected patients with inotrope-dependent heart failure. Yet, this technology does not come without significant risk of adverse effects and burdens. Recent observational data comparing LVAD with medical therapy in ambulatory, noninotrope-dependent patients with advanced heart failure suggest that survival may be similar and changes in quality of life may depend on baseline status. As both LVAD technology and medical therapy continue to evolve, there are many unanswered questions regarding the benefits, risks, and burdens of LVAD therapies in less severe heart failure populations. SUMMARY: Further research is needed to ensure the optimal delivery of LVAD therapy, including improved patient selection, implantation timing, device type, and decision support. VIDEO ABSTRACT.
Authors: Keith D Aaronson; Mark S Slaughter; Leslie W Miller; Edwin C McGee; William G Cotts; Michael A Acker; Mariell L Jessup; Igor D Gregoric; Pranav Loyalka; O H Frazier; Valluvan Jeevanandam; Allen S Anderson; Robert L Kormos; Jeffrey J Teuteberg; Wayne C Levy; David C Naftel; Richard M Bittman; Francis D Pagani; David R Hathaway; Steven W Boyce Journal: Circulation Date: 2012-05-22 Impact factor: 29.690
Authors: James N Kirkpatrick; Katherine Kellom; Sarah C Hull; Rebecca Henderson; Jasmeet Singh; Laura A Coyle; Maria Mountis; Elizabeth D Shore; Ralph Petrucci; Peter F Cronholm; Frances K Barg Journal: J Card Fail Date: 2015-06-09 Impact factor: 5.712
Authors: David Feldman; Salpy V Pamboukian; Jeffrey J Teuteberg; Emma Birks; Katherine Lietz; Stephanie A Moore; Jeffrey A Morgan; Francisco Arabia; Mary E Bauman; Hoger W Buchholz; Mario Deng; Marc L Dickstein; Aly El-Banayosy; Tonya Elliot; Daniel J Goldstein; Kathleen L Grady; Kylie Jones; Katarzyna Hryniewicz; Ranjit John; Annemarie Kaan; Shimon Kusne; Matthias Loebe; M Patricia Massicotte; Nader Moazami; Paul Mohacsi; Martha Mooney; Thomas Nelson; Francis Pagani; William Perry; Evgenij V Potapov; J Eduardo Rame; Stuart D Russell; Erik N Sorensen; Benjamin Sun; Martin Strueber; Abeel A Mangi; Michael G Petty; Joseph Rogers Journal: J Heart Lung Transplant Date: 2013-02 Impact factor: 10.247
Authors: William K Cornwell; Takashi Tarumi; Abigail Stickford; Justin Lawley; Monique Roberts; Rosemary Parker; Catherine Fitzsimmons; Julius Kibe; Colby Ayers; David Markham; Mark H Drazner; Qi Fu; Benjamin D Levine Journal: Circulation Date: 2015-10-28 Impact factor: 29.690
Authors: Matthew C Iacovetto; Daniel D Matlock; Colleen K McIlvennan; Jocelyn S Thompson; William Bradley; Shane J LaRue; Larry A Allen Journal: Circ Cardiovasc Qual Outcomes Date: 2014-10-14
Authors: Shannon M Dunlay; Soon J Park; Lyle D Joyce; Richard C Daly; John M Stulak; Sheila M McNallan; Véronique L Roger; Sudhir S Kushwaha Journal: J Heart Lung Transplant Date: 2013-12-27 Impact factor: 10.247
Authors: Mark S Slaughter; Joseph G Rogers; Carmelo A Milano; Stuart D Russell; John V Conte; David Feldman; Benjamin Sun; Antone J Tatooles; Reynolds M Delgado; James W Long; Thomas C Wozniak; Waqas Ghumman; David J Farrar; O Howard Frazier Journal: N Engl J Med Date: 2009-11-17 Impact factor: 91.245
Authors: Joseph G Rogers; Javed Butler; Steven L Lansman; Alan Gass; Peer M Portner; Michael K Pasque; Richard N Pierson Journal: J Am Coll Cardiol Date: 2007-08-06 Impact factor: 24.094
Authors: William K Cornwell; Takashi Tarumi; Vincent L Aengevaeren; Colby Ayers; Punag Divanji; Qi Fu; Dean Palmer; Mark H Drazner; Dan M Meyer; Brian T Bethea; Jeffrey L Hastings; Naoki Fujimoto; Shigeki Shibata; Rong Zhang; David W Markham; Benjamin D Levine Journal: J Heart Lung Transplant Date: 2014-08-28 Impact factor: 10.247
Authors: Amrut V Ambardekar; Michelle M Kittleson; Maryse Palardy; Maria M Mountis; Rhondalyn C Forde-McLean; Adam D DeVore; Salpy V Pamboukian; Jennifer T Thibodeau; Jeffrey J Teuteberg; Linda Cadaret; Rongbing Xie; Wendy Taddei-Peters; David C Naftel; James K Kirklin; Lynne W Stevenson; Garrick C Stewart Journal: J Heart Lung Transplant Date: 2018-10-01 Impact factor: 10.247
Authors: Amrut V Ambardekar; Jennifer T Thibodeau; Adam D DeVore; Michelle M Kittleson; Rhondalyn C Forde-McLean; Maryse Palardy; Maria M Mountis; Linda Cadaret; Jeffrey J Teuteberg; Salpy V Pamboukian; Rongbing Xie; Lynne W Stevenson; Garrick C Stewart Journal: JACC Heart Fail Date: 2017-08-16 Impact factor: 12.035
Authors: David M Harmon; Kristen M Tecson; Aayla K Jamil; Joost Felius; Gonzalo V Gonzalez-Stawinski; Susan M Joseph; Shelley A Hall Journal: Proc (Bayl Univ Med Cent) Date: 2019-03-28
Authors: Khadijah Breathett; Larry A Allen; Laura Helmkamp; Kathryn Colborn; Stacie L Daugherty; Irene V Blair; Jacqueline Jones; Prateeti Khazanie; Sula Mazimba; Marylyn McEwen; Jeff Stone; Elizabeth Calhoun; Nancy K Sweitzer; Pamela N Peterson Journal: Circ Heart Fail Date: 2018-08 Impact factor: 8.790
Authors: Khadijah Breathett; Larry A Allen; Laura Helmkamp; Kathryn Colborn; Stacie L Daugherty; Prateeti Khazanie; Richard Lindrooth; Pamela N Peterson Journal: JACC Heart Fail Date: 2017-01-18 Impact factor: 12.035