Literature DB >> 26889806

Parkinson's Disease: A Thalamostriatal Rebalancing Act?

Nicolas X Tritsch1, Adam G Carter2.   

Abstract

Motor impairments in Parkinson's disease are thought to result from hypoactivation of striatal projection neurons in the direct pathway. In this issue of Neuron, Parker et al. (2016) report that dopamine depletion selectively weakens thalamic but not cortical afferents onto these neurons, implicating the thalamus as playing a key role in Parkinsonian motor symptoms.
Copyright © 2016 Elsevier Inc. All rights reserved.

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Year:  2016        PMID： 26889806      PMCID： PMC6986164          DOI： 10.1016/j.neuron.2016.02.008

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  15 in total

1.  Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry.

Authors:  Alexxai V Kravitz; Benjamin S Freeze; Philip R L Parker; Kenneth Kay; Myo T Thwin; Karl Deisseroth; Anatol C Kreitzer
Journal:  Nature       Date:  2010-07-07       Impact factor: 49.962

2.  Striatal Cholinergic Interneurons Control Motor Behavior and Basal Ganglia Function in Experimental Parkinsonism.

Authors:  Nicolas Maurice; Martine Liberge; Florence Jaouen; Samira Ztaou; Marwa Hanini; Jeremy Camon; Karl Deisseroth; Marianne Amalric; Lydia Kerkerian-Le Goff; Corinne Beurrier
Journal:  Cell Rep       Date:  2015-10-17       Impact factor: 9.423

3.  Corticostriatal and thalamostriatal synapses have distinctive properties.

Authors:  Jun Ding; Jayms D Peterson; D James Surmeier
Journal:  J Neurosci       Date:  2008-06-18       Impact factor: 6.167

Review 4.  The functional anatomy of basal ganglia disorders.

Authors:  R L Albin; A B Young; J B Penney
Journal:  Trends Neurosci       Date:  1989-10       Impact factor: 13.837

5.  Rapid target-specific remodeling of fast-spiking inhibitory circuits after loss of dopamine.

Authors:  Aryn H Gittis; Giao B Hang; Eva S LaDow; Liza R Shoenfeld; Bassam V Atallah; Steven Finkbeiner; Anatol C Kreitzer
Journal:  Neuron       Date:  2011-09-08       Impact factor: 17.173

Review 6.  Dopaminergic modulation of synaptic transmission in cortex and striatum.

Authors:  Nicolas X Tritsch; Bernardo L Sabatini
Journal:  Neuron       Date:  2012-10-04       Impact factor: 17.173

7.  Cocaine exposure reorganizes cell type- and input-specific connectivity in the nucleus accumbens.

Authors:  Andrew F MacAskill; John M Cassel; Adam G Carter
Journal:  Nat Neurosci       Date:  2014-08-10       Impact factor: 24.884

8.  Pathway-Specific Remodeling of Thalamostriatal Synapses in Parkinsonian Mice.

Authors:  Philip R L Parker; Arnaud L Lalive; Anatol C Kreitzer
Journal:  Neuron       Date:  2016-01-28       Impact factor: 17.173

9.  Heterogeneous properties of central lateral and parafascicular thalamic synapses in the striatum.

Authors:  T J Ellender; J Harwood; P Kosillo; M Capogna; J P Bolam
Journal:  J Physiol       Date:  2012-10-29       Impact factor: 5.182

10.  Balanced activity in basal ganglia projection pathways is critical for contraversive movements.

Authors:  Fatuel Tecuapetla; Sara Matias; Guillaume P Dugue; Zachary F Mainen; Rui M Costa
Journal:  Nat Commun       Date:  2014-07-08       Impact factor: 14.919
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  4 in total

1.  Involvement of Striatal Cholinergic Interneurons and M1 and M4 Muscarinic Receptors in Motor Symptoms of Parkinson's Disease.

Authors:  Samira Ztaou; Nicolas Maurice; Jeremy Camon; Gaëlle Guiraudie-Capraz; Lydia Kerkerian-Le Goff; Corinne Beurrier; Martine Liberge; Marianne Amalric
Journal:  J Neurosci       Date:  2016-08-31       Impact factor: 6.167

Review 2.  Maladaptive Synaptic Plasticity in L-DOPA-Induced Dyskinesia.

Authors:  Qiang Wang; Wangming Zhang
Journal:  Front Neural Circuits       Date:  2016-12-20       Impact factor: 3.492

3.  Axonal degeneration in Parkinson's disease - Basal ganglia circuitry and D2 receptor availability.

Authors:  Esther Annegret Pelzer; Corina Melzer; Anna Schönberger; Martin Hess; Lars Timmermann; Carsten Eggers; Marc Tittgemeyer
Journal:  Neuroimage Clin       Date:  2019-06-21       Impact factor: 4.881

Review 4.  Neurochemical changes in basal ganglia affect time perception in parkinsonians.

Authors:  Francisco Magalhães; Kaline Rocha; Victor Marinho; Jéssica Ribeiro; Thomaz Oliveira; Carla Ayres; Thalys Bento; Francisca Leite; Daya Gupta; Victor Hugo Bastos; Bruna Velasques; Pedro Ribeiro; Marco Orsini; Silmar Teixeira
Journal:  J Biomed Sci       Date:  2018-03-19       Impact factor: 8.410
  4 in total

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