| Literature DB >> 26889138 |
Tarek El-Ghazaly1, Chad Ellimoottil1, John Wheeler1, Larissa Bresler1.
Abstract
The association between the development of bladder cancer and chronic bladder irritation is well established in the literature. Chronic urinary tract irritation can be the result of bacterial infections, foreign bodies, trauma of repeated catheterization, neurogenic bladder, urolithiasis, or chronic bladder outlet obstruction, all which have been implicated in the pathogenesis of non-bilharzial squamous cell carcinoma of the bladder (SCC). With many of the aforementioned factors present in patients with spinal cord injury, several retrospective studies have demonstrated a 16-28 fold increased relative risk of bladder cancer, with SCC accounting for 10 times more cases of bladder cancer compared to the general population. In this report, we present the case of incidentally-discovered SCC of the bladder found within sphincter/prostate chips of a patient with neurogenic bladder due to spinal cord injury n clean intermittent catheterization ho underwent sphincterotomy with negative cystoscopic findings.Entities:
Keywords: Bladder cancer; Catheterization complication; Cystoscopy; Spinal cord injury; Squamous cell carcinoma
Year: 2015 PMID: 26889138 PMCID: PMC4748808 DOI: 10.1159/000365710
Source DB: PubMed Journal: Curr Urol ISSN: 1661-7649