Literature DB >> 26889023

Structural Basis for Norovirus Inhibition by Human Milk Oligosaccharides.

Stefan Weichert1, Anna Koromyslova2,3, Bishal K Singh2,3, Satoko Hansman1,2, Stefan Jennewein4, Horst Schroten1, Grant S Hansman5,3.   

Abstract

Histo-blood group antigens (HBGAs) are important binding factors for norovirus infections. We show that two human milk oligosaccharides, 2'-fucosyllactose (2'FL) and 3-fucosyllactose (3FL), could block norovirus from binding to surrogate HBGA samples. We found that 2'FL and 3FL bound at the equivalent HBGA pockets on the norovirus capsid using X-ray crystallography. Our data revealed that 2'FL and 3FL structurally mimic HBGAs. These results suggest that 2'FL and 3FL might act as naturally occurring decoys in humans.
Copyright © 2016, American Society for Microbiology. All Rights Reserved.

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Year:  2016        PMID： 26889023      PMCID： PMC4836343          DOI： 10.1128/JVI.03223-15

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  27 in total

1.  Noroviruses bind to human ABO, Lewis, and secretor histo-blood group antigens: identification of 4 distinct strain-specific patterns.

Authors:  Pengwei Huang; Tibor Farkas; Séverine Marionneau; Weiming Zhong; Nathalie Ruvoën-Clouet; Ardythe L Morrow; Mekibib Altaye; Larry K Pickering; David S Newburg; Jacques LePendu; Xi Jiang
Journal:  J Infect Dis       Date:  2003-06-12       Impact factor: 5.226

2.  Stereochemical quality of protein structure coordinates.

Authors:  A L Morris; M W MacArthur; E G Hutchinson; J M Thornton
Journal:  Proteins       Date:  1992-04

3.  Norovirus and histo-blood group antigens: demonstration of a wide spectrum of strain specificities and classification of two major binding groups among multiple binding patterns.

Authors:  Pengwei Huang; Tibor Farkas; Weiming Zhong; Ming Tan; Scott Thornton; Ardythe L Morrow; Xi Jiang
Journal:  J Virol       Date:  2005-06       Impact factor: 5.103

Review 4.  Norovirus and its histo-blood group antigen receptors: an answer to a historical puzzle.

Authors:  Ming Tan; Xi Jiang
Journal:  Trends Microbiol       Date:  2005-06       Impact factor: 17.079

5.  Binding of Norwalk virus-like particles to ABH histo-blood group antigens is blocked by antisera from infected human volunteers or experimentally vaccinated mice.

Authors:  Patrick R Harrington; Lisa Lindesmith; Boyd Yount; Christine L Moe; Ralph S Baric
Journal:  J Virol       Date:  2002-12       Impact factor: 5.103

6.  Association of histo-blood group antigens and susceptibility to norovirus infections.

Authors:  Barry H G Rockx; Harry Vennema; Christian J P A Hoebe; Erwin Duizer; Marion P G Koopmans
Journal:  J Infect Dis       Date:  2005-01-25       Impact factor: 5.226

Review 7.  Oligosaccharides in human milk: structural, functional, and metabolic aspects.

Authors:  C Kunz; S Rudloff; W Baier; N Klein; S Strobel
Journal:  Annu Rev Nutr       Date:  2000       Impact factor: 11.848

8.  Human milk contains elements that block binding of noroviruses to human histo-blood group antigens in saliva.

Authors:  Xi Jiang; Pengwei Huang; Weiming Zhong; Ming Tan; Tibor Farkas; Ardythe L Morrow; David S Newburg; Guillermo M Ruiz-Palacios; Larry K Pickering
Journal:  J Infect Dis       Date:  2004-10-11       Impact factor: 5.226

9.  Human milk oligosaccharides are associated with protection against diarrhea in breast-fed infants.

Authors:  Ardythe L Morrow; Guillermo M Ruiz-Palacios; Mekibib Altaye; Xi Jiang; M Lourdes Guerrero; Jareen K Meinzen-Derr; Tibor Farkas; Prasoon Chaturvedi; Larry K Pickering; David S Newburg
Journal:  J Pediatr       Date:  2004-09       Impact factor: 4.406

10.  Structural basis for the recognition of blood group trisaccharides by norovirus.

Authors:  Sheng Cao; Zhiyong Lou; Ming Tan; Yutao Chen; Yijin Liu; Zhushan Zhang; Xuejun C Zhang; Xi Jiang; Xuemei Li; Zihe Rao
Journal:  J Virol       Date:  2007-03-28       Impact factor: 5.103
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  52 in total

1.  Like mother, like microbe: human milk oligosaccharide mediated microbiome symbiosis.

Authors:  Schuyler A Chambers; Steven D Townsend
Journal:  Biochem Soc Trans       Date:  2020-06-30       Impact factor: 5.407

2.  Milk Oligosaccharides Inhibit Human Rotavirus Infectivity in MA104 Cells.

Authors:  Daniel R Laucirica; Vassilis Triantis; Ruud Schoemaker; Mary K Estes; Sasirekha Ramani
Journal:  J Nutr       Date:  2017-06-21       Impact factor: 4.798

3.  Nanobody-Mediated Neutralization Reveals an Achilles Heel for Norovirus.

Authors:  Anna D Koromyslova; Jessica M Devant; Turgay Kilic; Charles D Sabin; Virginie Malak; Grant S Hansman
Journal:  J Virol       Date:  2020-06-16       Impact factor: 5.103

4.  Avidity of α-fucose on human milk oligosaccharides and blood group-unrelated oligo/polyfucoses is essential for potent norovirus-binding targets.

Authors:  Franz-Georg Hanisch; Grant S Hansman; Vasily Morozov; Clemens Kunz; Horst Schroten
Journal:  J Biol Chem       Date:  2018-06-01       Impact factor: 5.157

Review 5.  Structural features of glycan recognition among viral pathogens.

Authors:  Sreejesh Shanker; Liya Hu; Sasirekha Ramani; Robert L Atmar; Mary K Estes; B V Venkataram Prasad
Journal:  Curr Opin Struct Biol       Date:  2017-06-04       Impact factor: 6.809

6.  Atomic Structure of the Murine Norovirus Protruding Domain and Soluble CD300lf Receptor Complex.

Authors:  Turgay Kilic; Anna Koromyslova; Virginie Malak; Grant S Hansman
Journal:  J Virol       Date:  2018-05-14       Impact factor: 5.103

7.  Human Norovirus Neutralized by a Monoclonal Antibody Targeting the Histo-Blood Group Antigen Pocket.

Authors:  Anna D Koromyslova; Vasily A Morozov; Lisa Hefele; Grant S Hansman
Journal:  J Virol       Date:  2019-02-19       Impact factor: 5.103

8.  Structural Basis for Human Norovirus Capsid Binding to Bile Acids.

Authors:  Turgay Kilic; Anna Koromyslova; Grant S Hansman
Journal:  J Virol       Date:  2019-01-04       Impact factor: 5.103

Review 9.  Human Genetic Determinants of Viral Diseases.

Authors:  Adam D Kenney; James A Dowdle; Leonia Bozzacco; Temet M McMichael; Corine St Gelais; Amanda R Panfil; Yan Sun; Larry S Schlesinger; Matthew Z Anderson; Patrick L Green; Carolina B López; Brad R Rosenberg; Li Wu; Jacob S Yount
Journal:  Annu Rev Genet       Date:  2017-08-30       Impact factor: 16.830

Review 10.  Human Norovirus Interactions with Histo-Blood Group Antigens and Human Milk Oligosaccharides.

Authors:  Horst Schroten; Franz-Georg Hanisch; Grant S Hansman
Journal:  J Virol       Date:  2016-06-10       Impact factor: 5.103
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