Xiao-Ping Ren1,2,3. 1. Hand and Microsurgical Center, The Second Affiliated Hospital of Harbin Medical University, Harbin, China. 2. State-Province Key Laboratories of Biomedicine-Pharmaceutics, Harbin Medical University, Harbin, China. 3. Department of Molecular Pharmacology & Therapeutics, Stritch School of Medicine, Loyola University Chicago, Chicago, IL, USA.