Donald E Fry1,2. 1. 1 Department of Surgery, Northwestern University Feinberg School of Medicine , Chicago, Illinois. 2. 2 Department of Surgery, University of New Mexico School of Medicine , Albuquerque, New Mexico .
Abstract
BACKGROUND: Mechanical bowel preparation continues to be a controversial subject for the pre-operative management of patients undergoing elective colon resection. METHODS: The English literature on bowel preparation was searched to identify pertinent publications. RESULTS: The published literature over the past 80 y confirms that mechanical bowel preparation alone does not reduce surgical site infections. However, the use of appropriate oral antibiotics following mechanical bowel preparation with pre-operative systemic antibiotics reduces rates of surgical site infections and anastomotic leaks when compared with systemic antibiotics alone. CONCLUSIONS: Mechanical bowel preparation with pre-operative oral antibiotics and pre-operative systemic antibiotics are the standard of care for elective colon surgery. Refinement in methods of bowel preparation needs additional clinical investigations to further enhance outcomes.
BACKGROUND:Mechanical bowel preparation continues to be a controversial subject for the pre-operative management of patients undergoing elective colon resection. METHODS: The English literature on bowel preparation was searched to identify pertinent publications. RESULTS: The published literature over the past 80 y confirms that mechanical bowel preparation alone does not reduce surgical site infections. However, the use of appropriate oral antibiotics following mechanical bowel preparation with pre-operative systemic antibiotics reduces rates of surgical site infections and anastomotic leaks when compared with systemic antibiotics alone. CONCLUSIONS:Mechanical bowel preparation with pre-operative oral antibiotics and pre-operative systemic antibiotics are the standard of care for elective colon surgery. Refinement in methods of bowel preparation needs additional clinical investigations to further enhance outcomes.
Authors: Demetrios Moris; Jeffery Chakedis; Amir A Rahnemai-Azar; Ana Wilson; Mairead Marion Hennessy; Antonios Athanasiou; Eliza W Beal; Chrysoula Argyrou; Evangelos Felekouras; Timothy M Pawlik Journal: J Gastrointest Surg Date: 2017-07-06 Impact factor: 3.452
Authors: Dirk Van de Putte; Christelle Demarquay; Elke Van Daele; Lara Moussa; Christian Vanhove; Marc Benderitter; Wim Ceelen; Piet Pattyn; Noëlle Mathieu Journal: Cell Transplant Date: 2017-12 Impact factor: 4.064