Literature DB >> 2688554

Selective biotransformations. Patents and literature.

J S Dordick1.   

Abstract

Stereo- and regioselective biotransformations is an area of intense research interest. The ability to take advantage of microorganisms and isolated enzyme systems to perform selective organic syntheses is well known. In recent years, several new methodologies have caused a rapid growth in the area of selective biotransformations. These novel techniques include genetic and protein engineering, biocatalysis in organic media, improved screening procedures, as well as an increased awareness of the value of biotechnology to solve important problems in organic synthesis. Recent US patents and scientific literature on stereo- and regioselective biotransformations are surveyed. Patent abstracts are summarized individually and a list of literature references are given.

Mesh：

Year:  1989        PMID： 2688554     DOI： 10.1007/bf02921767

Source DB:  PubMed          Journal:  Appl Biochem Biotechnol        ISSN： 0273-2289            Impact factor:   2.926


  24 in total

1.  One-Step Microbial Conversion of a Racemic Mixture of Pantoyl Lactone to Optically Active d-(-)-Pantoyl Lactone.

Authors:  S Shimizu; S Hattori; H Hata; H Yamada
Journal:  Appl Environ Microbiol       Date:  1987-03       Impact factor: 4.792

2.  Bacillus cereus phospholipase C: carboxylic acid ester specificity and stereoselectivity.

Authors:  W R Snyder
Journal:  Biochim Biophys Acta       Date:  1987-07-31

3.  Stereoselective inhibition of calmodulin-dependent cAMP phosphodiesterase from bovine heart by (+)- and (-)-nimodipine.

Authors:  C Schächtele; B Wagner; D Marmé
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1987-03       Impact factor: 3.000

4.  Stereoselective formation and hydration of benzo[c]phenanthrene 3,4- and 5,6-epoxide enantiomers by rat liver microsomal enzymes.

Authors:  S K Yang; M Mushtaq; H B Weems
Journal:  Arch Biochem Biophys       Date:  1987-05-15       Impact factor: 4.013

5.  Stereoselectivity and enantioselectivity of glutathione S-transferase toward stilbene oxide substrates.

Authors:  P C deSmidt; M A McCarrick; J N Darnow; M Mervic; R N Armstrong
Journal:  Biochem Int       Date:  1987-03

6.  Stereoselectivity of naphthalene epoxidation by mouse, rat, and hamster pulmonary, hepatic, and renal microsomal enzymes.

Authors:  A R Buckpitt; N Castagnoli; S D Nelson; A D Jones; L S Bahnson
Journal:  Drug Metab Dispos       Date:  1987 Jul-Aug       Impact factor: 3.922

7.  Stereoselective formation and hydration of 12-methylbenz[a]anthracene 5,6-epoxide enantiomers by rat liver microsomal enzymes.

Authors:  S K Yang; M Mushtaq; H B Weems; D W Miller; P P Fu
Journal:  Biochem J       Date:  1987-07-01       Impact factor: 3.857

8.  Enzymes and catalysts. II. Pig liver esterase-catalyzed asymmetric synthesis of (-)- and (+)-cucurbitine and its (-)-thio analogue.

Authors:  Y Morimoto; K Achiwa
Journal:  Chem Pharm Bull (Tokyo)       Date:  1987-09       Impact factor: 1.645

9.  Regioselective and stereoselective metabolisms of pyrene and 1-bromopyrene by rat liver microsomes and effects of enzyme inducers.

Authors:  M Shou; S K Yang
Journal:  Drug Metab Dispos       Date:  1988 Mar-Apr       Impact factor: 3.922

10.  The stereoselectivity of the Clostridium perfringens phospholipase C: hydrolysis of thiophosphate analogs of phosphatidylcholine.

Authors:  G P Riedy; W R Snyder
Journal:  Arch Biochem Biophys       Date:  1987-11-01       Impact factor: 4.013
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