Shunlan Ni1, Shanshan Li1, Naibin Yang1, Sainan Zhang1, Danping Hu2, Qian Li3, Mingqin Lu1. 1. Department of Infectious Diseases, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou Key Laboratory of Hepatology, Hepatologic Institute of Wenzhou Medical University Wenzhou, Zhejiang, P. R. China. 2. Department of Infectious Diseases, Ruian City People's Hospital, The Third Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, P. R. China. 3. Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University Wenzhou, Zhejiang, P. R. China.
Abstract
BACKGROUND: Acinetobacter baumannii (A. baumannii), a gram-negative bacterium, has now become an important hospital pathogen, which causes various serious nosocomial infections worldwide. Bacterial meningitis is a common complication after neurosurgical operation, and the percentage of A. baumannii meningitis is growing, especially the one resisting multiple drugs. METHOD: We retrospectively reviewed the cases with postoperative A. baumannii meningitis (PABM) in the First Affiliated Hospital of Wenzhou Medical University from January 2013 to October 2014. And we retrieved the PubMed for cases with PABM and reviewed them. RESULT: Five cases were included in our retrospective study. Two cases with sensitive A. baumannii and one with multidrug-resistant acinetobacter baumannii (MRAB) were cured, and other two with MRAB died. CONCLUSION: Intraventricular or intrathecal colistin could be a treatment to the MRAB.
BACKGROUND:Acinetobacter baumannii (A. baumannii), a gram-negative bacterium, has now become an important hospital pathogen, which causes various serious nosocomial infections worldwide. Bacterial meningitis is a common complication after neurosurgical operation, and the percentage of A. baumannii meningitis is growing, especially the one resisting multiple drugs. METHOD: We retrospectively reviewed the cases with postoperative A. baumannii meningitis (PABM) in the First Affiliated Hospital of Wenzhou Medical University from January 2013 to October 2014. And we retrieved the PubMed for cases with PABM and reviewed them. RESULT: Five cases were included in our retrospective study. Two cases with sensitive A. baumannii and one with multidrug-resistant acinetobacter baumannii (MRAB) were cured, and other two with MRAB died. CONCLUSION: Intraventricular or intrathecal colistin could be a treatment to the MRAB.
Authors: M E Jiménez-Mejías; J Pachón; B Becerril; J Palomino-Nicás; A Rodríguez-Cobacho; M Revuelta Journal: Clin Infect Dis Date: 1997-05 Impact factor: 9.079