Literature DB >> 26884410

Use of an Implantable Loop Recorder in a Chimpanzee (Pan troglodytes) to Monitor Cardiac Arrhythmias and Assess the Effects of Acupuncture and Laser Therapy.

Elizabeth R Magden1, Meg M Sleeper2, Stephanie J Buchl3, Rebekah A Jones3, Erica J Thiele3, Gregory K Wilkerson3.   

Abstract

Cardiovascular disease is a leading cause of death in captive chimpanzees and is often associated with myocardial fibrosis, which increases the risk of cardiac arrhythmias. In this case report, we present a 36-y-old male chimpanzee (Pan troglodytes) diagnosed with frequent ventricular premature complexes (VPC). We placed a subcutaneous implantable loop recorder for continual ECG monitoring to assess his arrhythmias without the confounding effects of anesthetics. During his initial treatment with the antiarrhythmia medication amiodarone, he developed thrombocytopenia, and the drug was discontinued. After reviewing other potential therapies for the treatment of cardiac arrhythmias, we elected to try acupuncture and laser therapy in view of the positive results and the lack of adverse side effects reported in humans. We used 2 well-known cardiac acupuncture sites on the wrist, PC6 (pericardium 6) and HT7 (heart 7), and evaluated the results of the therapy by using the ECG recordings from the implantable loop recorder. Although periodic increases in the animal's excitement level introduced confounding variables that caused some variation in the data, acupuncture and laser therapy appeared to decrease the mean number of VPC/min in this chimpanzee.

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Year:  2016        PMID: 26884410      PMCID: PMC4752036     

Source DB:  PubMed          Journal:  Comp Med        ISSN: 1532-0820            Impact factor:   0.982


  26 in total

1.  Cardiovascular and endocrine effects of acupuncture in hypertensive patients.

Authors:  Y J Chiu; A Chi; I A Reid
Journal:  Clin Exp Hypertens       Date:  1997-10       Impact factor: 1.749

Review 2.  Mechanisms of cardiac fibrosis in inflammatory heart disease.

Authors:  Gabriela Kania; Przemyslaw Blyszczuk; Urs Eriksson
Journal:  Trends Cardiovasc Med       Date:  2009-11       Impact factor: 6.677

3.  Electrocardiogram abnormalities in captive chimpanzees (Pan troglodytes).

Authors:  Cynthia J Doane; D Rick Lee; Meg M Sleeper
Journal:  Comp Med       Date:  2006-12       Impact factor: 0.982

4.  Fatal arrhythmogenic right ventricular cardiomyopathy in 2 related subadult chimpanzees (Pan troglodytes).

Authors:  L J Tong; E J Flach; M N Sheppard; A Pocknell; A A Banerjee; A Boswood; T Bouts; A Routh; Y Feltrer
Journal:  Vet Pathol       Date:  2013-08-29       Impact factor: 2.221

5.  Amiodarone-induced thrombocytopenia.

Authors:  I Weinberger; Z Rotenberg; J Fuchs; E Ben-Sasson; J Agmon
Journal:  Arch Intern Med       Date:  1987-04

6.  Acupuncture as an adjunct therapy for osteoarthritis in chimpanzees (Pan troglodytes).

Authors:  Elizabeth R Magden; Rachel L Haller; Erica J Thiele; Stephanie J Buchl; Susan P Lambeth; Steven J Schapiro
Journal:  J Am Assoc Lab Anim Sci       Date:  2013-07       Impact factor: 1.232

7.  Echocardiography parameters of clinically normal adult captive chimpanzees (Pan troglodytes).

Authors:  Meg M Sleeper; Ken Drobatz; D Richard Lee; Michael L Lammey
Journal:  J Am Vet Med Assoc       Date:  2014-04-15       Impact factor: 1.936

8.  Heart disease is common in humans and chimpanzees, but is caused by different pathological processes.

Authors:  Nissi Varki; Dan Anderson; James G Herndon; Tho Pham; Christopher J Gregg; Monica Cheriyan; James Murphy; Elizabeth Strobert; Jo Fritz; James G Else; Ajit Varki
Journal:  Evol Appl       Date:  2009-02       Impact factor: 5.183

9.  Rest perfusion abnormalities in hypertrophic cardiomyopathy: correlation with myocardial fibrosis and risk factors for sudden cardiac death.

Authors:  A Chiribiri; S Leuzzi; M R Conte; S Bongioanni; K Bratis; L Olivotti; C De Rosa; E Lardone; P Di Donna; A D M Villa; F Cesarani; E Nagel; F Gaita; R Bonamini
Journal:  Clin Radiol       Date:  2015-02-07       Impact factor: 2.350

10.  Acupuncture effect and central autonomic regulation.

Authors:  Qian-Qian Li; Guang-Xia Shi; Qian Xu; Jing Wang; Cun-Zhi Liu; Lin-Peng Wang
Journal:  Evid Based Complement Alternat Med       Date:  2013-05-26       Impact factor: 2.629

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  4 in total

1.  The implementation and initial evaluation of a physical therapy program for captive chimpanzees (Pan troglodytes).

Authors:  Sarah J Neal Webb; Jennifer P Bridges; Erica Thiele; Susan P Lambeth; Steven J Schapiro
Journal:  Am J Primatol       Date:  2020-02-20       Impact factor: 2.371

2.  Differences in Behavior Between Elderly and Nonelderly Captive Chimpanzees and the Effects of the Social Environment.

Authors:  Sarah J Neal Webb; Jann Hau; Susan P Lambeth; Steven J Schapiro
Journal:  J Am Assoc Lab Anim Sci       Date:  2019-10-23       Impact factor: 1.232

3.  Cardioprotection of Electroacupuncture for Enhanced Recovery after Surgery on Patients Undergoing Heart Valve Replacement with Cardiopulmonary Bypass: A Randomized Control Clinical Trial.

Authors:  Fangxiang Zhang; Xiangdi Yu; Hong Xiao
Journal:  Evid Based Complement Alternat Med       Date:  2017-02-16       Impact factor: 2.629

Review 4.  Spotlight on acupuncture in laboratory animal medicine.

Authors:  Elizabeth R Magden
Journal:  Vet Med (Auckl)       Date:  2017-08-24
  4 in total

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