Literature DB >> 26882830

Chemotherapy near the end of life; assessment of the clinical practise in onco-hematological in adult patients.

Pilar Taberner Bonastre1, María Teresa Taberner Bonastre2, Enrique Soler Company1, María Dolores Pérez-Serrano Lainosa1.   

Abstract

OBJECTIVE: ensure a good quality of life in the last phase of onco- hematological patients should be the primary goal, despite this, we have little data at European level and published studies are contradictory. Nevertheless, most of them agree saying that administrating chemotherapy near the end of life impacts negatively in the patients quality of life. The main objective of this study is to analyze the treatment non-aggressiveness parameters in onco-hematological patients. The secondary objective is to do a describing study of the clinical variables of the patients who receive chemotherapy at the end of life and the treatments more used.
METHODS: a retrospective observational study was conducted in a tertiary hospital. Both, oncological and hematological patients receiving chemotherapy (oral or intravenous) between January and December 2013 who were receiving chemotherapy in the last 90 days before death, were included.
RESULTS: there were 823 patients that were threated between January and December of 2013. Of these 106 (13%) met the inclusion criteria to be analyzed. There were a 14.1% (n = 93) of oncological and a 8.4% (n = 13) of hematologic patients that maintained the antineoplasic treatment during the last three months before death. A 21.7% (n = 23) of the patients received chemotherapy in the last two weeks of life, 41.5% (n = 44) in the last 30 days and 78.3% (n = 83) in the last two months of life. There was a 67.9% (n = 72) of patients that had hospital admissions during their last three months of life, 47,2% (n = 50) during the last month, 33% (n = 35) during the last two weeks and 10,4% (n = 11) during the last three days of life. A 25,5% (n = 27) of patients had more than one hospital admission during their last 90 days.
CONCLUSIONS: according to the Earle et al. criteria, our population had been treated aggressively. We need more scientific evidence with consolidate date that allows us to establish a unified criteria for the selection of patients with advanced cancer who may benefit from receiving antineoplasic treatments. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.

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Year:  2016        PMID: 26882830     DOI: 10.7399/fh.2016.40.1.8918

Source DB:  PubMed          Journal:  Farm Hosp        ISSN: 1130-6343


  5 in total

1.  Aggressiveness of end-of-life cancer care: what happens in clinical practice?

Authors:  Estela García-Martín; Vicente Escudero-Vilaplana; Bárbara Fox; Roberto Collado-Borrell; Belén Marzal-Alfaro; María Sánchez-Isac; María Luisa Solano-Garzón; Ricardo González Del Val; José Manuel Cano-González; Nuria Pérez de Lucas; Ana Isabel Bravo-Guillén; Javier Valero-Salinas; Eva González-Haba; María Sanjurjo; Miguel Martín
Journal:  Support Care Cancer       Date:  2020-10-16       Impact factor: 3.603

2.  Care of cancer patients at the end of life in a German university hospital: A retrospective observational study from 2014.

Authors:  Burkhard Dasch; Helen Kalies; Berend Feddersen; Caecilie Ruderer; Wolfgang Hiddemann; Claudia Bausewein
Journal:  PLoS One       Date:  2017-04-06       Impact factor: 3.240

3.  Timing of palliative care referral and aggressive cancer care toward the end-of-life in pancreatic cancer: a retrospective, single-center observational study.

Authors:  Natasha Michael; Greta Beale; Clare O'Callaghan; Adelaide Melia; William DeSilva; Daniel Costa; David Kissane; Jeremy Shapiro; Richard Hiscock
Journal:  BMC Palliat Care       Date:  2019-01-28       Impact factor: 3.234

4.  Changes of End of Life Practices for Cancer Patients and Their Association with Hospice Palliative Care Referral over 2009-2014: A Single Institution Study.

Authors:  Hyun Jung Jho; Eun Jung Nam; Il Won Shin; Sun Young Kim
Journal:  Cancer Res Treat       Date:  2019-09-03       Impact factor: 4.679

5.  Quality of life in women treated with chemotherapy for breast cancer in Cali, Colombia

Authors:  María Elena Mejía-Rojas; Adolfo Contreras-Rengifo; Mauricio Hernández-Carrillo
Journal:  Biomedica       Date:  2020-06-15       Impact factor: 0.935

  5 in total

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