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Literature DB >> 26882253

A PTENtial cause for the selectivity of oncolytic viruses?

Brian R Champion¹, Kerry Fisher², Len Seymour³.

Abstract

Mesh：

Substances：

Year: 2016 PMID： 26882253 DOI： 10.1038/ni.3394

Source DB: PubMed Journal: Nat Immunol ISSN： 1529-2908 Impact factor: 25.606

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12 in total

1. Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation.

Authors: Laura Poliseno; Leonardo Salmena; Luisa Riccardi; Alessandro Fornari; Min Sup Song; Robin M Hobbs; Paolo Sportoletti; Shorheh Varmeh; Ainara Egia; Giuseppe Fedele; Lucia Rameh; Massimo Loda; Pier Paolo Pandolfi
Journal: Sci Signal Date: 2010-04-13 Impact factor: 8.192

2. The tumor suppressor PTEN has a critical role in antiviral innate immunity.

Authors: Shun Li; Mingzhu Zhu; Ruangang Pan; Ting Fang; Yuan-Yuan Cao; Shuliang Chen; Xiaolu Zhao; Cao-Qi Lei; Lin Guo; Yu Chen; Chun-Mei Li; Eija Jokitalo; Yuxin Yin; Hong-Bing Shu; Deyin Guo
Journal: Nat Immunol Date: 2015-12-21 Impact factor: 25.606

Review 3. Mutations of the human PTEN gene.

Authors: D Bonneau; M Longy
Journal: Hum Mutat Date: 2000 Impact factor: 4.878

4. Promoter methylation of the PTEN gene is a common molecular change in breast cancer.

Authors: Jose M García; Javier Silva; Cristina Peña; Vanesa Garcia; Rufo Rodríguez; Miguel A Cruz; Blanca Cantos; Mariano Provencio; Pilar España; Felix Bonilla
Journal: Genes Chromosomes Cancer Date: 2004-10 Impact factor: 5.006

5. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

Authors: Katherine A Fitzgerald; Sarah M McWhirter; Kerrie L Faia; Daniel C Rowe; Eicke Latz; Douglas T Golenbock; Anthony J Coyle; Sha-Mei Liao; Tom Maniatis
Journal: Nat Immunol Date: 2003-05 Impact factor: 25.606

Review 6. The role of differential expression of human interferon--a genes in antiviral immunity.

Authors: Pierre Génin; Alexandra Vaccaro; Ahmet Civas
Journal: Cytokine Growth Factor Rev Date: 2009-08-03 Impact factor: 7.638

7. Induction of protein kinase PKR-dependent activation of interferon regulatory factor 3 by vaccinia virus occurs through adapter IPS-1 signaling.

Authors: Ping Zhang; Charles E Samuel
Journal: J Biol Chem Date: 2008-10-15 Impact factor: 5.157

8. Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation.

Authors: Siqi Liu; Xin Cai; Jiaxi Wu; Qian Cong; Xiang Chen; Tuo Li; Fenghe Du; Junyao Ren; You-Tong Wu; Nick V Grishin; Zhijian J Chen
Journal: Science Date: 2015-01-29 Impact factor: 47.728

9. MGMT promoter hypermethylation and K-RAS, PTEN and TP53 mutations in tamoxifen-exposed and non-exposed endometrial cancer cases.

Authors: E Nagy; K B Gajjar; I I Patel; S Taylor; P L Martin-Hirsch; H F Stringfellow; F L Martin; D H Phillips
Journal: Br J Cancer Date: 2014-05-22 Impact factor: 7.640

10. Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway.

Authors: Katie Twigger; Victoria Roulstone; Joan Kyula; Eleni M Karapanagiotou; Konstantinos N Syrigos; Richard Morgan; Christine White; Shreerang Bhide; Gerard Nuovo; Matt Coffey; Brad Thompson; Adel Jebar; Fiona Errington; Alan A Melcher; Richard G Vile; Hardev S Pandha; Kevin J Harrington
Journal: BMC Cancer Date: 2012-08-24 Impact factor: 4.430

7 in total

7. Enhanced cytotoxicity of reovirus and radiotherapy in melanoma cells is mediated through increased viral replication and mitochondrial apoptotic signalling.

Authors: Gráinne McEntee; Joan N Kyula; David Mansfield; Henry Smith; Michelle Wilkinson; Claire Gregory; Victoria Roulstone; Matt Coffey; Kevin J Harrington
Journal: Oncotarget Date: 2016-07-26

7 in total

A PTENtial cause for the selectivity of oncolytic viruses?

1. Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation.

2. The tumor suppressor PTEN has a critical role in antiviral innate immunity.

Review 3. Mutations of the human PTEN gene.

4. Promoter methylation of the PTEN gene is a common molecular change in breast cancer.

5. IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.

Review 6. The role of differential expression of human interferon--a genes in antiviral immunity.

7. Induction of protein kinase PKR-dependent activation of interferon regulatory factor 3 by vaccinia virus occurs through adapter IPS-1 signaling.

8. Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation.

9. MGMT promoter hypermethylation and K-RAS, PTEN and TP53 mutations in tamoxifen-exposed and non-exposed endometrial cancer cases.

10. Reovirus exerts potent oncolytic effects in head and neck cancer cell lines that are independent of signalling in the EGFR pathway.

Review 1. The functions of tumor suppressor PTEN in innate and adaptive immunity.

Review 2. Cellular and molecular regulation of innate inflammatory responses.

3. Recent advances in vesicular stomatitis virus-based oncolytic virotherapy: a 5-year update.

Review 4. Clinical implications of PTEN loss in prostate cancer.

Review 5. Oncolytic virus delivery: from nano-pharmacodynamics to enhanced oncolytic effect.

Review 6. Is there a causal link between PTEN deficient tumors and immunosuppressive tumor microenvironment?

7. Enhanced cytotoxicity of reovirus and radiotherapy in melanoma cells is mediated through increased viral replication and mitochondrial apoptotic signalling.