Literature DB >> 26882252

The NEK-sus of the NLRP3 inflammasome.

Filip Van Hauwermeiren1, Mohamed Lamkanfi1.   

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Year:  2016        PMID: 26882252     DOI: 10.1038/ni.3391

Source DB:  PubMed          Journal:  Nat Immunol        ISSN: 1529-2908            Impact factor:   25.606


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  12 in total

Review 1.  Mechanisms and functions of inflammasomes.

Authors:  Mohamed Lamkanfi; Vishva M Dixit
Journal:  Cell       Date:  2014-05-22       Impact factor: 41.582

2.  Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome.

Authors:  H M Hoffman; J L Mueller; D H Broide; A A Wanderer; R D Kolodner
Journal:  Nat Genet       Date:  2001-11       Impact factor: 38.330

3.  Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death.

Authors:  Jianjin Shi; Yue Zhao; Kun Wang; Xuyan Shi; Yue Wang; Huanwei Huang; Yinghua Zhuang; Tao Cai; Fengchao Wang; Feng Shao
Journal:  Nature       Date:  2015-09-16       Impact factor: 49.962

4.  Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling.

Authors:  Nobuhiko Kayagaki; Irma B Stowe; Bettina L Lee; Karen O'Rourke; Keith Anderson; Søren Warming; Trinna Cuellar; Benjamin Haley; Merone Roose-Girma; Qui T Phung; Peter S Liu; Jennie R Lill; Hong Li; Jiansheng Wu; Sarah Kummerfeld; Juan Zhang; Wyne P Lee; Scott J Snipas; Guy S Salvesen; Lucy X Morris; Linda Fitzgerald; Yafei Zhang; Edward M Bertram; Christopher C Goodnow; Vishva M Dixit
Journal:  Nature       Date:  2015-09-16       Impact factor: 49.962

5.  Cryopyrin activates the inflammasome in response to toxins and ATP.

Authors:  Sanjeev Mariathasan; David S Weiss; Kim Newton; Jacqueline McBride; Karen O'Rourke; Meron Roose-Girma; Wyne P Lee; Yvette Weinrauch; Denise M Monack; Vishva M Dixit
Journal:  Nature       Date:  2006-01-11       Impact factor: 49.962

6.  Critical role for Cryopyrin/Nalp3 in activation of caspase-1 in response to viral infection and double-stranded RNA.

Authors:  Thirumala-Devi Kanneganti; Mathilde Body-Malapel; Amal Amer; Jong-Hwan Park; Joel Whitfield; Luigi Franchi; Zenobia F Taraporewala; David Miller; John T Patton; Naohiro Inohara; Gabriel Núñez
Journal:  J Biol Chem       Date:  2006-09-28       Impact factor: 5.157

7.  Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1.

Authors:  Fayyaz S Sutterwala; Yasunori Ogura; Marian Szczepanik; Maria Lara-Tejero; G Scott Lichtenberger; Ethan P Grant; John Bertin; Anthony J Coyle; Jorge E Galán; Philip W Askenase; Richard A Flavell
Journal:  Immunity       Date:  2006-03       Impact factor: 31.745

8.  NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder.

Authors:  Laetitia Agostini; Fabio Martinon; Kimberly Burns; Michael F McDermott; Philip N Hawkins; Jürg Tschopp
Journal:  Immunity       Date:  2004-03       Impact factor: 31.745

9.  A Genome-wide CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) Screen Identifies NEK7 as an Essential Component of NLRP3 Inflammasome Activation.

Authors:  Jonathan L Schmid-Burgk; Dhruv Chauhan; Tobias Schmidt; Thomas S Ebert; Julia Reinhardt; Elmar Endl; Veit Hornung
Journal:  J Biol Chem       Date:  2015-11-09       Impact factor: 5.157

10.  A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.

Authors:  Rebecca C Coll; Avril A B Robertson; Jae Jin Chae; Sarah C Higgins; Raúl Muñoz-Planillo; Marco C Inserra; Irina Vetter; Lara S Dungan; Brian G Monks; Andrea Stutz; Daniel E Croker; Mark S Butler; Moritz Haneklaus; Caroline E Sutton; Gabriel Núñez; Eicke Latz; Daniel L Kastner; Kingston H G Mills; Seth L Masters; Kate Schroder; Matthew A Cooper; Luke A J O'Neill
Journal:  Nat Med       Date:  2015-02-16       Impact factor: 53.440

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  10 in total

1.  Licochalcone B specifically inhibits the NLRP3 inflammasome by disrupting NEK7-NLRP3 interaction.

Authors:  Qiang Li; Hui Feng; Hongbo Wang; Yinghao Wang; Wenqing Mou; Guang Xu; Ping Zhang; Ruisheng Li; Wei Shi; Zhilei Wang; Zhie Fang; Lutong Ren; Yan Wang; Li Lin; Xiaorong Hou; Wenzhang Dai; Zhiyong Li; Ziying Wei; Tingting Liu; Jiabo Wang; Yuming Guo; Pengyan Li; Xu Zhao; Xiaoyan Zhan; Xiaohe Xiao; Zhaofang Bai
Journal:  EMBO Rep       Date:  2021-12-09       Impact factor: 8.807

2.  Deep Learning and Structure-Based Virtual Screening for Drug Discovery against NEK7: A Novel Target for the Treatment of Cancer.

Authors:  Mubashir Aziz; Syeda Abida Ejaz; Seema Zargar; Naveed Akhtar; Abdullahi Tunde Aborode; Tanveer A Wani; Gaber El-Saber Batiha; Farhan Siddique; Mohammed Alqarni; Ashraf Akintayo Akintola
Journal:  Molecules       Date:  2022-06-25       Impact factor: 4.927

Review 3.  Activation and Regulation of NLRP3 by Sterile and Infectious Insults.

Authors:  Srijon K Banerjee; Ayan Chatterjee; Shamba Gupta; Abhinit Nagar
Journal:  Front Immunol       Date:  2022-05-12       Impact factor: 8.786

Review 4.  Role of NLRP3 inflammasome in systemic sclerosis.

Authors:  Cong Lin; Zhixing Jiang; Ling Cao; Hejian Zou; Xiaoxia Zhu
Journal:  Arthritis Res Ther       Date:  2022-08-16       Impact factor: 5.606

5.  Inhibition of the NLRP3 inflammasome can prevent sterile intra-amniotic inflammation, preterm labor/birth, and adverse neonatal outcomes†.

Authors:  Nardhy Gomez-Lopez; Roberto Romero; Valeria Garcia-Flores; Yaozhu Leng; Derek Miller; Sonia S Hassan; Chaur-Dong Hsu; Bogdan Panaitescu
Journal:  Biol Reprod       Date:  2019-05-01       Impact factor: 4.285

6.  Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction.

Authors:  Yi Zhang; Xuehua Lv; Zizhong Hu; Xiaojian Ye; Xinhua Zheng; Yuzhi Ding; Ping Xie; Qinghuai Liu
Journal:  Cell Death Dis       Date:  2017-07-20       Impact factor: 8.469

7.  Actin organization and endocytic trafficking are controlled by a network linking NIMA-related kinases to the CDC-42-SID-3/ACK1 pathway.

Authors:  Vladimir Lažetić; Braveen B Joseph; Sarina M Bernazzani; David S Fay
Journal:  PLoS Genet       Date:  2018-04-02       Impact factor: 5.917

8.  MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice.

Authors:  Agampodi Promoda Perera; Ruchira Fernando; Tanvi Shinde; Rohit Gundamaraju; Benjamin Southam; Sukhwinder Singh Sohal; Avril A B Robertson; Kate Schroder; Dale Kunde; Rajaraman Eri
Journal:  Sci Rep       Date:  2018-06-05       Impact factor: 4.379

Review 9.  Mechanisms of Endothelial Dysfunction in Pre-eclampsia and Gestational Diabetes Mellitus: Windows Into Future Cardiometabolic Health?

Authors:  Colm J McElwain; Eszter Tuboly; Fergus P McCarthy; Cathal M McCarthy
Journal:  Front Endocrinol (Lausanne)       Date:  2020-09-11       Impact factor: 5.555

10.  Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis.

Authors:  Lindsey Mayes-Hopfinger; Aura Enache; Jian Xie; Chou-Long Huang; Robert Köchl; Victor L J Tybulewicz; Teresa Fernandes-Alnemri; Emad S Alnemri
Journal:  Nat Commun       Date:  2021-07-27       Impact factor: 14.919

  10 in total

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