| Literature DB >> 2688204 |
N Koch, J Lipp, U Pessara, K Schenck, C Wraight, B Dobberstein.
Abstract
Most protein antigens cannot elicit a T-cell response unless they are processed to peptides, which are then presented to T lymphocytes by surface MHC class II molecules. Recent evidence supports an essential role of the invariant chain associated with class II MHC polypeptides in antigen processing.Mesh:
Substances:
Year: 1989 PMID: 2688204 DOI: 10.1016/0968-0004(89)90013-3
Source DB: PubMed Journal: Trends Biochem Sci ISSN: 0968-0004 Impact factor: 13.807