Literature DB >> 26880379

The potential of methylxanthine-based therapies in pediatric respiratory tract diseases.

Ainhoa Oñatibia-Astibia1, Eva Martínez-Pinilla2, Rafael Franco3.   

Abstract

Caffeine, theophylline and theobromine are the most known methylxanthines as they are present in coffee, tea and/or chocolate. In the last decades, a huge experimental effort has been devoted to get insight into the variety of actions that these compounds exert in humans. From such knowledge it is known that methylxanthines have a great potential in prevention, therapy and/or management of a variety of diseases. The benefits of methylxanthine-based therapies in the apnea of prematurity and their translational potential in pediatric affections of the respiratory tract are here presented.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Airways; Apnea of prematurity; Asthma; Caffeine; Cough; Theobromine; Theophylline; Xanthine

Mesh：

Substances：

Year:  2016        PMID： 26880379     DOI： 10.1016/j.rmed.2016.01.022

Source DB:  PubMed          Journal:  Respir Med        ISSN： 0954-6111            Impact factor:   3.415


  19 in total

1.  Effects of Theophylline with Methylprednisolone Combination Therapy on Biomechanics and Histopathology in Diaphragm Muscles of Rats.

Authors:  Nureddin Yuzkat; Ismail Kati; Yasemin Isik; Servet Kavak; Ugur Goktas; Nurettin Cengiz
Journal:  Inflammation       Date:  2016-10       Impact factor: 4.092

2.  A Study on the Synbiotic Composition of Bifidobacterium bifidum and Fructans from Arctium lappa Roots and Helianthus tuberosus Tubers against Staphylococcus aureus.

Authors:  Svetlana A Evdokimova; Vera S Nokhaeva; Boris A Karetkin; Elena V Guseva; Natalia V Khabibulina; Maria A Kornienko; Veronika D Grosheva; Natalia V Menshutina; Irina V Shakir; Victor I Panfilov
Journal:  Microorganisms       Date:  2021-04-26

3.  Zebrafish Embryo as an In Vivo Model for Behavioral and Pharmacological Characterization of Methylxanthine Drugs.

Authors:  Ram Manohar Basnet; Michela Guarienti; Maurizio Memo
Journal:  Int J Mol Sci       Date:  2017-03-09       Impact factor: 5.923

4.  Caffeine modulates glucocorticoid-induced expression of CTGF in lung epithelial cells and fibroblasts.

Authors:  Markus Fehrholz; Kirsten Glaser; Christian P Speer; Silvia Seidenspinner; Barbara Ottensmeier; Steffen Kunzmann
Journal:  Respir Res       Date:  2017-03-23

5.  Caffeine to prevent respiratory failure and improve outcome in infant pertussis.

Authors:  John Evered; Eric Pfeifer; Matthew Gracianette
Journal:  BMJ Case Rep       Date:  2018-03-28

6.  A Novel, Pan-PDE Inhibitor Exerts Anti-Fibrotic Effects in Human Lung Fibroblasts via Inhibition of TGF-β Signaling and Activation of cAMP/PKA Signaling.

Authors:  Katarzyna Wójcik-Pszczoła; Grażyna Chłoń-Rzepa; Agnieszka Jankowska; Marietta Ślusarczyk; Paweł E Ferdek; Agnieszka A Kusiak; Artur Świerczek; Krzysztof Pociecha; Paulina Koczurkiewicz-Adamczyk; Elżbieta Wyska; Elżbieta Pękala; Reinoud Gosens
Journal:  Int J Mol Sci       Date:  2020-06-03       Impact factor: 5.923

7.  Effect of Caffeine and Other Methylxanthines on Aβ-Homeostasis in SH-SY5Y Cells.

Authors:  Daniel Janitschke; Christopher Nelke; Anna Andrea Lauer; Liesa Regner; Jakob Winkler; Andrea Thiel; Heike Sabine Grimm; Tobias Hartmann; Marcus Otto Walter Grimm
Journal:  Biomolecules       Date:  2019-11-02

8.  Unique Role of Caffeine Compared to Other Methylxanthines (Theobromine, Theophylline, Pentoxifylline, Propentofylline) in Regulation of AD Relevant Genes in Neuroblastoma SH-SY5Y Wild Type Cells.

Authors:  Daniel Janitschke; Anna A Lauer; Cornel M Bachmann; Martin Seyfried; Heike S Grimm; Tobias Hartmann; Marcus O W Grimm
Journal:  Int J Mol Sci       Date:  2020-11-27       Impact factor: 5.923

Review 9.  Microglial Adenosine Receptors: From Preconditioning to Modulating the M1/M2 Balance in Activated Cells.

Authors:  Rafael Franco; Alejandro Lillo; Rafael Rivas-Santisteban; Irene Reyes-Resina; Gemma Navarro
Journal:  Cells       Date:  2021-05-07       Impact factor: 6.600

10.  Antileukotrienes for the prevention and treatment of chronic lung disease in very preterm newborns: a systematic review.

Authors:  Marlide Jukema; Franciszek Borys; Greta Sibrecht; Karsten Juhl Jørgensen; Matteo Bruschettini
Journal:  Respir Res       Date:  2021-07-17
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