Firat Uygur1, Hakan Tanriverdi2, Ziyaeddin Aktop3, Fatma Erboy2, Bulent Altinsoy2, Murat Damar4, Figen Atalay2. 1. Bulent Ecevit University, Faculty of Medicine, Department of Pulmonary Medicine, Zonguldak, Turkey. Electronic address: dr.fuygur@hotmail.com. 2. Bulent Ecevit University, Faculty of Medicine, Department of Pulmonary Medicine, Zonguldak, Turkey. 3. Bulent Ecevit University, Faculty of Medicine, Department of Cardiology, Zonguldak, Turkey. 4. Bulent Ecevit University, Faculty of Medicine, Department of Otolaryngology, Zonguldak, Turkey.
Abstract
OBJECTIVE: To investigate the association between the neutrophil-to-lymphocyte ratio (NLR) and obstructive sleep apnoea syndrome (OSAS) severity and whether the NLR predicts cardiovascular disease (CVD) in patients with OSAS. BACKGROUND: OSAS is known as a risk factor for CVD. An increased NLR was strongly correlated with cardiovascular outcomes in several studies. METHODS: We retrospectively examined the laboratory data for 289 patients with suspected OSAS evaluated using polysomnography. RESULTS: The study included 171 OSAS patients and 118 controls. The NLR was higher in OSAS group than control group. The NLR was significantly higher in patients with CVD than in those without (3.31 ± 1.1 vs. 1.93 ± 0.8, p = 0.002). There were also significant correlations between the NLR and apnoea-hypopnoea index, mean SaO2, and oxygen desaturation index. CONCLUSIONS: There was a significant correlation between the NLR and OSAS severity and the NLR was independently associated with CVD in patients with OSAS.
OBJECTIVE: To investigate the association between the neutrophil-to-lymphocyte ratio (NLR) and obstructive sleep apnoea syndrome (OSAS) severity and whether the NLR predicts cardiovascular disease (CVD) in patients with OSAS. BACKGROUND: OSAS is known as a risk factor for CVD. An increased NLR was strongly correlated with cardiovascular outcomes in several studies. METHODS: We retrospectively examined the laboratory data for 289 patients with suspected OSAS evaluated using polysomnography. RESULTS: The study included 171 OSAS patients and 118 controls. The NLR was higher in OSAS group than control group. The NLR was significantly higher in patients with CVD than in those without (3.31 ± 1.1 vs. 1.93 ± 0.8, p = 0.002). There were also significant correlations between the NLR and apnoea-hypopnoea index, mean SaO2, and oxygen desaturation index. CONCLUSIONS: There was a significant correlation between the NLR and OSAS severity and the NLR was independently associated with CVD in patients with OSAS.
Authors: Moh'd Al-Halawani; Christian Kyung; Fei Liang; Ian Kaplan; Jane Moon; Guerrier Clerger; Bruce Sabin; Andrea Barnes; Mohammad Al-Ajam Journal: J Clin Sleep Med Date: 2020-01-13 Impact factor: 4.062
Authors: Glaucylara Reis Geovanini; Rui Wang; Jia Weng; Russell Tracy; Nancy S Jenny; Ary L Goldberger; Madalena D Costa; Yongmei Liu; Peter Libby; Susan Redline Journal: Int J Cardiol Date: 2018-04-15 Impact factor: 4.039