| Literature DB >> 26879483 |
Yukihiro Horio1, Takahisa Takihara2, Kyoko Niimi3, Masamichi Komatsu4, Masako Sato5, Jun Tanaka6, Hiroto Takiguchi7, Hiromi Tomomatsu8, Katsuyoshi Tomomatsu9, Naoki Hayama10, Tsuyoshi Oguma11, Takuya Aoki12, Tetsuya Urano13, Atsushi Takagi14, Koichiro Asano15.
Abstract
We report 3 cases (all men, age: 69-81 years) of acute exacerbation of interstitial pneumonia (AEIP) that were successfully treated with a high-flow nasal cannula (HFNC), which delivers heated, humidified gas at a fraction of inspired oxygen (FIO2) up to 1.0 (100%). Oxygenation was insufficient under non-rebreathing face masks; however, the introduction of HFNC with an FIO2 of 0.7-1.0 (flow rate: 40 L/min) improved oxygenation and was well-tolerated until the partial pressure of oxygen in blood/FIO2 ratio increased (between 21 and 26 days). Thus, HFNC might be an effective and well-tolerated therapeutic addition to the management of AEIP.Entities:
Keywords: Acute exacerbation; Acute respiratory failure; High-flow nasal cannula; Interstitial pneumonia; Oxygen therapy
Mesh：
Year: 2015 PMID： 26879483 DOI： 10.1016/j.resinv.2015.09.005
Source DB: PubMed Journal: Respir Investig ISSN： 2212-5345