Deevakar Rogith1, Rafeek A Yusuf1, Shelley R Hovick2, Bryan M Fellman3, Susan K Peterson3, Allison M Burton-Chase4, Yisheng Li3, Elmer V Bernstam5, Funda Meric-Bernstam6. 1. The University of Texas School of Biomedical Informatics, Houston, TX 77030, United States. 2. The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States; The Ohio State University, Columbus, OH 43210, United States. 3. The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States. 4. The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States; Albany College of Pharmacy and Health Sciences, Albany, NY 12208, United States. 5. The University of Texas School of Biomedical Informatics, Houston, TX 77030, United States; Division of General Internal Medicine, Department of Internal Medicine, The University of Texas Health Science Center at Houston, TX 77030, United States. 6. The University of Texas MD Anderson Cancer Center, Houston, TX 77030, United States. Electronic address: fmeric@mdanderson.org.
Abstract
BACKGROUND: Understanding patients' knowledge and prior information-seeking regarding personalized cancer therapy (PCT) may inform future patient information systems, consent for molecular testing and PCT protocols. We evaluated breast cancer patients' knowledge and information-seeking behaviors regarding PCT. METHODS: Newly registered female breast cancer patients (n=100) at a comprehensive cancer center completed a self-administered questionnaire prior to their first clinic visit. RESULTS: Knowledge regarding cancer genetics and PCT was moderate (mean 8.7±3.8 questions correct out of 16). A minority of patients (27%) indicated that they had sought information regarding PCT. Higher education (p=0.009) and income levels (p=0.04) were associated with higher knowledge scores and with seeking PCT information (p=0.04). Knowledge was not associated with willingness to participate in PCT research. CONCLUSION: Educational background and financial status impact patient knowledge as well as information-seeking behavior. For most patients, clinicians are likely to be patients' initial source of information about PCT. Understanding patients' knowledge deficits at presentation may help inform patient education efforts.
BACKGROUND: Understanding patients' knowledge and prior information-seeking regarding personalized cancer therapy (PCT) may inform future patient information systems, consent for molecular testing and PCT protocols. We evaluated breast cancerpatients' knowledge and information-seeking behaviors regarding PCT. METHODS: Newly registered female breast cancerpatients (n=100) at a comprehensive cancer center completed a self-administered questionnaire prior to their first clinic visit. RESULTS: Knowledge regarding cancer genetics and PCT was moderate (mean 8.7±3.8 questions correct out of 16). A minority of patients (27%) indicated that they had sought information regarding PCT. Higher education (p=0.009) and income levels (p=0.04) were associated with higher knowledge scores and with seeking PCT information (p=0.04). Knowledge was not associated with willingness to participate in PCT research. CONCLUSION: Educational background and financial status impact patient knowledge as well as information-seeking behavior. For most patients, clinicians are likely to be patients' initial source of information about PCT. Understanding patients' knowledge deficits at presentation may help inform patient education efforts.
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