| Literature DB >> 26878486 |
Miroslava Martinková1, Jozef Gonda2.
Abstract
Conformationally constrained sphingolipids such as anhydrophytosphingosines represented by jaspine B (also known as pachastrissamine) and its stereoisomers have become an attractive and timely target for total synthesis due to their significant biological activity as well as the unique structures. This review article describes the biological activity and chemistry of the natural jaspine B and its seven stereoisomers.Entities:
Keywords: Anhydrophytosphingosines; Asymmetric synthesis; Cytotoxic activity; Jaspine B; Sphingolipids; Stereoselective synthesis
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Year: 2016 PMID： 26878486 DOI： 10.1016/j.carres.2016.01.009
Source DB: PubMed Journal: Carbohydr Res ISSN： 0008-6215 Impact factor: 2.104