BACKGROUND AND OBJECTIVE: To investigate the influence of age and central foveal thickness (CFT) on the foveal avascular zone (FAZ) size in healthy people using optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: A cross-section study. One hundred thirty-two healthy subjects (224 eyes) were included. All participants underwent examination with OCTA. CFT and FAZ size, including vertical radius (VR), horizontal radius (HR), and area, were measured. RESULTS: Linear regression analysis showed a positive correlation between age and FAZ size. The HR, VR, and area had an increase of 0.001 mm (P = .002), 0.001 mm (P = .001), and 0.001 mm(2) (P = .000) each year, respectively. There was a negative correlation between CFT and FAZ size. When the CFT increased per 1 µm, the HR, VR, and area decreased by 0.002 mm (P = .000), 0.001 mm (P = .000), and 0.003 mm(2) (P = .000), respectively. CONCLUSIONS: FAZ size increases with age and decreases with CFT. OCTA is a novel method to study the FAZ in healthy people. Copyright 2016, SLACK Incorporated.
BACKGROUND AND OBJECTIVE: To investigate the influence of age and central foveal thickness (CFT) on the foveal avascular zone (FAZ) size in healthy people using optical coherence tomography angiography (OCTA). PATIENTS AND METHODS: A cross-section study. One hundred thirty-two healthy subjects (224 eyes) were included. All participants underwent examination with OCTA. CFT and FAZ size, including vertical radius (VR), horizontal radius (HR), and area, were measured. RESULTS: Linear regression analysis showed a positive correlation between age and FAZ size. The HR, VR, and area had an increase of 0.001 mm (P = .002), 0.001 mm (P = .001), and 0.001 mm(2) (P = .000) each year, respectively. There was a negative correlation between CFT and FAZ size. When the CFT increased per 1 µm, the HR, VR, and area decreased by 0.002 mm (P = .000), 0.001 mm (P = .000), and 0.003 mm(2) (P = .000), respectively. CONCLUSIONS: FAZ size increases with age and decreases with CFT. OCTA is a novel method to study the FAZ in healthy people. Copyright 2016, SLACK Incorporated.
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