| Literature DB >> 26876808 |
Taoyuan He1, Di Li, Yanan Yang, Jianxun Ding, Feng Jin, Xiuli Zhuang, Xuesi Chen.
Abstract
Micelle with mesomeric polyleucine (PDLLeu) core demonstrated the most uniform morphology, the smallest diameter and the highest drug loading capability compared to those with dextrorotatory (PDLeu), levorotatory (PLLeu) and racemic PLeu (PD/LLeu) cores. In addition, the modification with c(RGDfC) endowed the optimal PDLLeu micelle with enhanced intracellular drug release and cytotoxicity, indicating its great potential for targeted drug delivery.Entities:
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Year: 2016 PMID： 26876808 DOI： 10.1039/c6bm00022c
Source DB: PubMed Journal: Biomater Sci ISSN： 2047-4830 Impact factor: 6.843