Literature DB >> 26876744

Early impact of rotavirus vaccination in a large paediatric hospital in the UK.

D Hungerford1, J M Read2, R P D Cooke3, R Vivancos4, M Iturriza-Gómara5, D J Allen6, N French5, N Cunliffe7.   

Abstract

The impact of routine rotavirus vaccination on community-acquired (CA) and healthcare-associated (HA) rotavirus gastroenteritis (RVGE) at a large paediatric hospital, UK, was investigated over a 13-year period. A total of 1644 hospitalized children aged 0-15 years tested positive for rotavirus between July 2002 and June 2015. Interrupted time-series analysis demonstrated that, post vaccine introduction (July 2013 to June 2015), CA- and HA-RVGE hospitalizations were 83% [95% confidence interval (CI): 72-90%) and 83% (95% CI: 66-92%] lower than expected, respectively. Rotavirus vaccination has rapidly reduced the hospital rotavirus disease burden among both CA- and HA-RVGE cases.
Copyright © 2016 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Epidemiology; Healthcare-associated infection; Rotavirus; Vaccination

Mesh:

Substances:

Year:  2015        PMID: 26876744     DOI: 10.1016/j.jhin.2015.12.010

Source DB:  PubMed          Journal:  J Hosp Infect        ISSN: 0195-6701            Impact factor:   3.926


  15 in total

Review 1.  Healthcare-associated infections: potential for prevention through vaccination.

Authors:  E David G McIntosh
Journal:  Ther Adv Vaccines Immunother       Date:  2018-03-14

2.  Trends in rotavirus from 2001 to 2015 in two paediatric hospitals in Atlanta, Georgia.

Authors:  B K Sederdahl; J Yi; R C Jerris; S E Gillespie; L F Westblade; C S Kraft; A L Shane; E J Anderson
Journal:  Epidemiol Infect       Date:  2018-02-12       Impact factor: 4.434

3.  Changes in the numbers of patients with acute gastroenteritis after voluntary introduction of the rotavirus vaccine in a Japanese children's primary emergency medical center.

Authors:  Ichiro Morioka; Naohiro Kamiyoshi; Masahiro Nishiyama; Tomohiko Yamamura; Shogo Minamikawa; Sota Iwatani; Hiroaki Nagase; Kandai Nozu; Noriyuki Nishimura; Mariko Taniguchi-Ikeda; Kazuto Ishibashi; Akihito Ishida; Kazumoto Iijima
Journal:  Environ Health Prev Med       Date:  2017-03-31       Impact factor: 3.674

4.  Viromic Analysis of Wastewater Input to a River Catchment Reveals a Diverse Assemblage of RNA Viruses.

Authors:  Evelien M Adriaenssens; Kata Farkas; Christian Harrison; David L Jones; Heather E Allison; Alan J McCarthy
Journal:  mSystems       Date:  2018-05-22       Impact factor: 6.496

5.  Incidence of household transmission of acute gastroenteritis (AGE) in a primary care sentinel network (1992-2017): cross-sectional and retrospective cohort study protocol.

Authors:  Simon de Lusignan; Emmanouela Konstantara; Mark Joy; Julian Sherlock; Uy Hoang; Rachel Coyle; Filipa Ferreira; Simon Jones; Sarah J O'Brien
Journal:  BMJ Open       Date:  2018-08-23       Impact factor: 2.692

6.  Do hospital pressures change following rotavirus vaccine introduction? A retrospective database analysis in a large paediatric hospital in the UK.

Authors:  Ellen Heinsbroek; Daniel Hungerford; Richard P D Cooke; Margaret Chowdhury; James S Cargill; Naor Bar-Zeev; Neil French; Eleni Theodorou; Baudouin Standaert; Nigel A Cunliffe
Journal:  BMJ Open       Date:  2019-05-15       Impact factor: 2.692

7.  Investigating awareness, fear and control associated with norovirus and other pathogens and pollutants using best-worst scaling.

Authors:  Kata Farkas; Emma Green; Dan Rigby; Paul Cross; Sean Tyrrel; Shelagh K Malham; David L Jones
Journal:  Sci Rep       Date:  2021-05-27       Impact factor: 4.379

8.  The Sustained Rotavirus Vaccination Impact on Nosocomial Infection, Duration of Hospital Stay, and Age: The RotaBIS Study (2005-2012).

Authors:  Baudouin Standaert; Danielle Strens; Xiao Li; Nadia Schecroun; Marc Raes
Journal:  Infect Dis Ther       Date:  2016-10-06

9.  Rotavirus vaccine impact and socioeconomic deprivation: an interrupted time-series analysis of gastrointestinal disease outcomes across primary and secondary care in the UK.

Authors:  Daniel Hungerford; Roberto Vivancos; Jonathan M Read; Miren Iturriza-Gόmara; Neil French; Nigel A Cunliffe
Journal:  BMC Med       Date:  2018-01-29       Impact factor: 8.775

10.  Estimating the Burden of Medically Attended Norovirus Gastroenteritis: Modeling Linked Primary Care and Hospitalization Datasets.

Authors:  Thomas Verstraeten; Tom Cattaert; John Harris; Ben Lopman; Clarence C Tam; Germano Ferreira
Journal:  J Infect Dis       Date:  2017-11-15       Impact factor: 5.226

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