| Literature DB >> 26875763 |
Michela Menegon1, Abduselam M Nurahmed2, Albadawi A Talha3, Bakri Y M Nour4, Carlo Severini5.
Abstract
The introduction of artemisinin-based combination therapy has led to extraordinary results in malaria control, however the recent emergence of partial resistance to artemisinin therapy in Southeast Asia jeopardizes these successes. This study aimed at investigating resistance to the antimalarial drugs by evaluating the polymorphisms in the PfK13, Pfcrt and Pfmdr1 genes in Plasmodium falciparum isolates obtained from patients in Eritrea.Entities:
Keywords: Drug resistance; Eritrea; Kelch 13 propeller; Pfcrt; Pfmdr1; Plasmodium falciparum
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Year: 2016 PMID： 26875763 DOI： 10.1016/j.actatropica.2016.02.007
Source DB: PubMed Journal: Acta Trop ISSN： 0001-706X Impact factor: 3.112