Literature DB >> 26874065

Numerical investigation of the mechanical properties of the additive manufactured bone scaffolds fabricated by FDM: The effect of layer penetration and post-heating.

S Naghieh1, M R Karamooz Ravari2, M Badrossamay1, E Foroozmehr3, M Kadkhodaei1.   

Abstract

In recent years, thanks to additive manufacturing technology, researchers have gone towards the optimization of bone scaffolds for the bone reconstruction. Bone scaffolds should have appropriate biological as well as mechanical properties in order to play a decisive role in bone healing. Since the fabrication of scaffolds is time consuming and expensive, numerical methods are often utilized to simulate their mechanical properties in order to find a nearly optimum one. Finite element analysis is one of the most common numerical methods that is used in this regard. In this paper, a parametric finite element model is developed to assess the effects of layers penetration׳s effect on inter-layer adhesion, which is reflected on the mechanical properties of bone scaffolds. To be able to validate this model, some compression test specimens as well as bone scaffolds are fabricated with biocompatible and biodegradable poly lactic acid using fused deposition modeling. All these specimens are tested in compression and their elastic modulus is obtained. Using the material parameters of the compression test specimens, the finite element analysis of the bone scaffold is performed. The obtained elastic modulus is compared with experiment indicating a good agreement. Accordingly, the proposed finite element model is able to predict the mechanical behavior of fabricated bone scaffolds accurately. In addition, the effect of post-heating of bone scaffolds on their elastic modulus is investigated. The results demonstrate that the numerically predicted elastic modulus of scaffold is closer to experimental outcomes in comparison with as-built samples.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Additive manufacturing; Bone scaffolds; Elastic modulus; Finite element analysis; Fused deposition modeling; Mechanical response

Mesh:

Year:  2016        PMID: 26874065     DOI: 10.1016/j.jmbbm.2016.01.031

Source DB:  PubMed          Journal:  J Mech Behav Biomed Mater        ISSN: 1878-0180


  9 in total

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Authors:  Nihal Engin Vrana; Sharda Gupta; Kunal Mitra; Albert A Rizvanov; Valeriya V Solovyeva; Ezgi Antmen; Majid Salehi; Arian Ehterami; Lea Pourchet; Julien Barthes; Christophe A Marquette; Magnus von Unge; Chi-Yun Wang; Po-Liang Lai; Arindam Bit
Journal:  Cell Tissue Bank       Date:  2022-01-09       Impact factor: 1.752

Review 2.  Bioprinting of Vascularized Tissue Scaffolds: Influence of Biopolymer, Cells, Growth Factors, and Gene Delivery.

Authors:  M D Sarker; Saman Naghieh; N K Sharma; Liqun Ning; Xiongbiao Chen
Journal:  J Healthc Eng       Date:  2019-04-02       Impact factor: 2.682

Review 3.  Effect of the nano/microscale structure of biomaterial scaffolds on bone regeneration.

Authors:  Lisha Zhu; Dan Luo; Yan Liu
Journal:  Int J Oral Sci       Date:  2020-02-06       Impact factor: 6.344

4.  Effect of 3D-Printed PLA Structure on Sound Reflection Properties.

Authors:  Katarina Monkova; Martin Vasina; Peter Pavol Monka; Jan Vanca; Dražan Kozak
Journal:  Polymers (Basel)       Date:  2022-01-20       Impact factor: 4.329

5.  Fabrication and Characterization of PCL/HA Filament as a 3D Printing Material Using Thermal Extrusion Technology for Bone Tissue Engineering.

Authors:  Fengze Wang; Esma Bahar Tankus; Francesco Santarella; Nadja Rohr; Neha Sharma; Sabrina Märtin; Mirja Michalscheck; Michaela Maintz; Shuaishuai Cao; Florian M Thieringer
Journal:  Polymers (Basel)       Date:  2022-02-11       Impact factor: 4.329

6.  Total and partial knee arthroplasty implants that maintain native load transfer in the tibia.

Authors:  Maxwell J Munford; Jennifer C Stoddart; Alexander D Liddle; Justin P Cobb; Jonathan R T Jeffers
Journal:  Bone Joint Res       Date:  2022-02       Impact factor: 5.853

7.  Three-dimensional printing of polycaprolactone/hydroxyapatite bone tissue engineering scaffolds mechanical properties and biological behavior.

Authors:  Naghme Rezania; Mitra Asadi-Eydivand; Nabiollah Abolfathi; Shahin Bonakdar; Morteza Mehrjoo; Mehran Solati-Hashjin
Journal:  J Mater Sci Mater Med       Date:  2022-03-10       Impact factor: 3.896

8.  Photopolymerized poly(l-lactide-b-N-vinyl-2-pyrrolidone) network resists cell adhesion in situ.

Authors:  Yong Wang; Xiaorong Lan; Shuyin Zuo; Yafeng Zou; Sai Li; Zhonglan Tang; Yunbing Wang
Journal:  RSC Adv       Date:  2021-06-14       Impact factor: 4.036

Review 9.  3D biofabrication of vascular networks for tissue regeneration: A report on recent advances.

Authors:  M D Sarker; Saman Naghieh; N K Sharma; Xiongbiao Chen
Journal:  J Pharm Anal       Date:  2018-08-28
  9 in total

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